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Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

A young man with high-grade prostate cancer had successful surgery and good recovery, highlighting the need for awareness in younger men.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.

Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Melatonin may reduce skin damage caused by X-rays in rats.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Finasteride may cause kidney damage.

Finasteride has a higher risk of reproductive side effects than minoxidil.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

CT scans can find serious prostate cancer even when PSA levels are low.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride may not affect gynecomastia recurrence after mastectomy.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

Finasteride for hair loss is safe and does not increase the risk of high-grade prostate cancer.