Finasteride and Methadone Use and Risk of Advanced Hepatitis C Related Liver Disease
June 2012
in “
Digestive Diseases and Sciences
”
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Studysummary This study suggests that finasteride use is not significantly associated with a reduced risk of advanced hepatic fibrosis or inflammation in HCV-positive males, with ethnically-divergent findings for methadone requiring further investigation. Our plain-language summary of this paper — not a Tressless recommendation.
The study aimed to investigate whether the use of finasteride for BPH and methadone for opiate addiction is associated with an increased risk of advanced hepatic fibrosis and inflammatory activity in HCV+ male veterans. The study recruited 571 male veterans with chronic HCV not receiving antiviral therapy at their scheduled primary care visit. The results showed that there was no significant association between the use of finasteride or methadone and the risk of advanced HCV-related liver disease. The study concluded that the use of finasteride or methadone does not increase the risk of advanced hepatic fibrosis or inflammatory activity in HCV+ male veterans.
