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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Male-pattern hair loss is normal, often involves hormone effects on hair follicles, and can be treated with medication or surgery, but new treatments are being researched.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Kalya Research is an AI tool that effectively finds and analyzes alternative medicine literature, saving researchers time.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Dosing time affects finasteride's effectiveness and safety in rats.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

New drugs for heart disease may be developed from molecules secreted by stem cells.

COVID-19 may harm male fertility and damage the reproductive system.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.