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No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

Women with a certain type of hair loss had lower levels of a hormone called prolactin compared to healthy women.

The compounds tested could potentially treat hair loss and alopecia.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Some common medications can harm male fertility, but many effects can be reversed.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.