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Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Prolactin slows down hair growth in mice.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.