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Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Certain gene variations might be linked to severe acne in women but not in men.

RANK-RANKL signaling is essential for hair growth and skin health.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Finasteride reduces movement issues in Parkinson's disease rats.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

New steroids were effective in blocking male hormone receptors in hamster prostates.