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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

PCOS is a long-term condition that needs more research for better understanding and treatment.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.

The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.