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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

Finasteride reduces hair growth and is safe for women with excessive hair.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

A natural steroid in the body may protect against eye damage in glaucoma.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

The normal human prostate does not significantly affect blood DHT levels.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.