November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” The workshop aimed to improve hair loss disorder diagnosis and understanding.
15 citations,
January 2019 in “International Journal of Women's Dermatology” Early treatment helps stop hair loss in women of color.
12 citations,
June 2015 in “Dermatology Reports” Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.
1 citations,
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.
74 citations,
July 2008 in “Dermatologic therapy” Early detection and histopathology are crucial to prevent permanent hair loss in cicatricial alopecia.
August 2023 in “Journal of The American Academy of Dermatology” Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.
January 2022 in “Clinical Cases in Dermatology” A condition called Central Centrifugal Cicatricial Alopecia causes hair loss and scalp burning in middle-aged African women, and it's treated with various medications, hair transplants, and non-drug methods like wigs.
4 citations,
May 2020 in “Journal of The American Academy of Dermatology” Cicatricial pattern hair loss is likely advanced common baldness, not a type of lichen planopilaris.
30 citations,
November 2013 in “Journal of The American Academy of Dermatology” Elastin staining helps assess late-stage scarring alopecia but is not definitive, and clinical diagnosis is still crucial.
12 citations,
January 2016 in “Skin appendage disorders” Hair restoration surgery can potentially treat primary scarring alopecias, but it's important to start early medication, ensure patient remission before transplant, and monitor after surgery.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
98 citations,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
44 citations,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
38 citations,
January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
November 2022 in “Frontiers in Medicine” PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.
48 citations,
May 2013 in “Canadian Medical Association Journal” Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.
28 citations,
August 2018 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) may help improve hair density in primary cicatricial alopecias (PCAs) patients, but more trials are needed to confirm its benefits.
January 2020 in “JAAD case reports” Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
27 citations,
September 2018 in “Skin appendage disorders” Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.
72 citations,
July 2008 in “Dermatologic Therapy” CCCA is a scarring hair loss condition mainly in African descent women, possibly caused by genetics and hairstyling, treated with gentle hair care and medications.
22 citations,
June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
5 citations,
July 2013 in “Our Dermatology Online” Lichen planopilaris is the most common type of scarring hair loss observed, with a variety of symptoms and tissue changes.
4 citations,
August 2010 in “Journal of the American Academy of Dermatology” Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
27 citations,
January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
2 citations,
January 2013 in “Hair therapy & transplantation” Hair transplants can be a treatment for scarring hair loss if there's good blood flow and no active disease.
June 2021 in “Journal of The American Academy of Dermatology” The "spade sign" is a highly specific indicator for diagnosing acne keloidalis.
64 citations,
June 2009 in “Journal of The American Academy of Dermatology” Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.
6 citations,
January 2017 in “British Journal of Dermatology” Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting older women, with no known cause and treatments that may help stabilize hair loss.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.