Cicatricial Alopecia in a 56-Year-Old Woman with Idiopathic Thrombocytopenic Purpura

    August 2010 in “ Journal of the American Academy of Dermatology ”
    Joshua M. Berlin, Anna L. Wang, Brandon C McDuffie, Douglas R. Leeman
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    TLDR Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
    The document discussed cicatricial alopecia, focusing on a 56-year-old woman with idiopathic thrombocytopenic purpura who presented with patchy hair loss over 2 years. Physical examination revealed scarring alopecia with central hypopigmentation and erythema. Diagnoses to consider included discoid lupus erythematosus, lichen planopilaris, and others. Histologic findings for discoid lupus erythematosus included lymphocytic interface dermatitis and follicular plugging. Treatment options ranged from intralesional and topical corticosteroids to systemic retinoids, methotrexate, and antimalarial agents, with isotretinoin and thalidomide for severe cases.
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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 2 weeks ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

      community Comprehensive Microneedling Guide

      in Microneedling  290 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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