Cicatricial Alopecia in a 56-Year-Old Woman with Idiopathic Thrombocytopenic Purpura

    August 2010 in “ Journal of the American Academy of Dermatology ”
    Joshua M. Berlin, Anna L. Wang, Brandon C McDuffie, Douglas R. Leeman
    Image of study
    TLDR Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
    The document discussed cicatricial alopecia, focusing on a 56-year-old woman with idiopathic thrombocytopenic purpura who presented with patchy hair loss over 2 years. Physical examination revealed scarring alopecia with central hypopigmentation and erythema. Diagnoses to consider included discoid lupus erythematosus, lichen planopilaris, and others. Histologic findings for discoid lupus erythematosus included lymphocytic interface dermatitis and follicular plugging. Treatment options ranged from intralesional and topical corticosteroids to systemic retinoids, methotrexate, and antimalarial agents, with isotretinoin and thalidomide for severe cases.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 17 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  94 upvotes 2 weeks ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 3 months ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

    Related Research

    4 / 4 results