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    GlossaryOral Retinoids (Systemic Retinoids)

    medications derived from vitamin A for severe skin conditions

    Oral retinoids are a class of medications derived from vitamin A, used to treat various skin conditions, including severe acne and psoriasis. They work by regulating cell growth and differentiation, which can help reduce inflammation and promote healthier skin. These medications can have significant side effects, so they are typically prescribed under strict medical supervision.

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      learn Fluridil

      a topical anti-androgen with less systemic involvement

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      highly targeted anti-androgen that might have minimal systemic effects

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      a synthetic estrogen used topically as an anti-androgen

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      community Hair shed after adding tretinoin with topical minoxydil

      in Minoxidil  3 upvotes 3 months ago
      Adding tretinoin to a minoxidil routine can cause initial hair shedding, which may be normal as it potentially increases minoxidil's efficacy. Users suggest being cautious with tretinoin application, especially around microneedling, to avoid increased systemic absorption.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Month 7. Dut/min/stemoxydine/microneedle. Nw7.

      in Progress Pictures  175 upvotes 3 weeks ago
      A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hair growth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.