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GlossaryAntimalarials

medications used to prevent and treat malaria infections

Antimalarials are medications used to prevent and treat malaria, a disease caused by parasites transmitted through the bites of infected mosquitoes. These drugs work by targeting different stages of the parasite's life cycle in the human body, thereby reducing the severity of the infection or preventing it altogether. Some antimalarials, such as hydroxychloroquine, are also used off-label to treat autoimmune conditions like lupus and rheumatoid arthritis due to their anti-inflammatory properties.

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research Therapeutic Updates on Lichen Planopilaris and Frontal Fibrosing Alopecia: A Systematic Review

September 2018

Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.

research Anticancer Agents Against Malaria: Time to Revisit?

39 citations, January 2010 in “Trends in Parasitology”

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents

20 citations, June 2022 in “Molecules”

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

research Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus: More Than a Coincidence

April 2019 in “Actas Dermo-Sifiliográficas”

The conclusion is that having both Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus may suggest a shared immune response in certain people, and a mix of antimalarial drugs and 5-alfa-reductase inhibitors is recommended for treatment.

research Cicatricial Alopecia in a 56-Year-Old Woman with Idiopathic Thrombocytopenic Purpura

4 citations, August 2010 in “Journal of the American Academy of Dermatology”

Cicatricial alopecia involves scarring hair loss and can be treated with various medications.

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