74 citations
,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” This review summarizes the cutaneous manifestations of lupus erythematosus, noting both non-specific and disease-specific lesions, and highlights the role of skin biopsies and treatments available for cutaneous LE.
30 citations
,
September 2005 in “Best Practice & Research Clinical Rheumatology” This review discusses therapies for skin lesions in lupus erythematosus and reports no new clinical results, focusing on defining and managing refractory disease.
4 citations
,
August 2010 in “Journal of the American Academy of Dermatology” This case report involves a 56-year-old woman with idiopathic thrombocytopenic purpura and scarring alopecia, suggesting diagnoses including discoid lupus erythematosus and lichen planopilaris without presenting new clinical findings.
This review found that antimalarial agents were more effective than steroids for Lichen planopilaris, while finasteride and dutasteride showed favorable impacts on frontal fibrosing alopecia, despite heterogeneous study quality.
February 2010 in “Emergency Medicine News” This case report describes a 36-year-old African American woman with discoid lupus resulting in skin lesions, highlighting the need for a multidisciplinary approach in managing cutaneous and systemic lupus symptoms.
18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
July 2018 in “Elsevier eBooks” This article reviews the clinical presentation, diagnosis, and treatment options for discoid lupus erythematosus and reports no new clinical results.
4 citations
,
May 1999 in “PubMed” This article reviews various drugs reported to cause alopecia, including cytostatics and anticoagulants, but does not present new research results; it suggests that drug-related hair loss can be difficult to prove.
39 citations
,
January 2010 in “Trends in Parasitology” This opinion article explores the possibility of repurposing anticancer drugs, like methotrexate, as antimalarials, highlighting that toxicity might be manageable with appropriate dosing according to Paracelsus' law.
April 2016 in “Journal of Investigative Dermatology” This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
January 2025 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This study investigated the effects of Christia vespertilionis extract on breast cancer cell lines, finding that it had a concentration-dependent cytotoxic effect, although less potent than tamoxifen, suggesting potential as an alternative cancer treatment.
October 1977 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This study found that telogen effluvium occurred in two subjects taking 500 mg of mefloquine weekly, and gastrointestinal intolerance was observed at higher doses in additional acute studies.
20 citations
,
June 2022 in “Molecules” This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.
20 citations
,
June 2021 in “British Journal of Dermatology” This review provides detailed recommendations for managing cutaneous lupus erythematosus in primary and secondary care but reports no new clinical results.
70 citations
,
July 2020 in “Pharmacological Reports” This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.
March 2023 in “Revista română de reumatologie” This article reviews the classification and treatment of cutaneous manifestations in systemic lupus erythematosus, highlighting the importance of monitoring for disease progression and reports no new clinical results.
June 2021 in “International Journal of Ayurvedic Medicine” This study found that humulen, a phytoconstituent of Cyperus Rotundus Linn., showed the highest binding affinity in molecular docking with the 5 α reductase enzyme, suggesting potential anti-androgenic effects for hirsutism treatment.
This review discusses various skin-related conditions affecting hair and nails, highlighting associations with systemic pathologies but reports no new clinical findings.
13 citations
,
October 2017 in “Biomedicine & Pharmacotherapy” In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.
January 2017 in “Springer eBooks” This article reviews the classification, pathogenesis, and treatment options for cutaneous lupus erythematosus and reports no new clinical findings.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” This study identified neprilysin as a potential target of the pharmacological agent arteannuin, which may guide future research into its clinical applications, although experimental verification is needed.
4 citations
,
August 2021 in “Annals of Translational Medicine” In this study, dihydroartemisinin reduced prostate enlargement and related markers in a rat model of benign prostatic hyperplasia, suggesting its potential as a therapeutic agent.
50 citations
,
May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
36 citations
,
April 2022 in “Nutrients” This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.
8 citations
,
September 2022 in “Biointerface Research in Applied Chemistry” This review examines the pharmacological potential of quinoline alkaloids from Cinchona bark for developing new drugs and cosmetics but reports no new findings.
20 citations
,
October 2018 in “American Journal of Clinical Dermatology” This article reviews drug-induced pigmentation and reports no new clinical findings, highlighting difficulty in confirming drug associations due to factors like delayed onset and polypharmacy.
February 2010 in “Journal of The American Academy of Dermatology” A woman with Degos disease managed her condition for nine years with medications and had two healthy pregnancies, while a separate finding suggests a possible link between female pattern hair loss and high blood pressure.
5 citations
,
May 2025 in “Scientific Reports” This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.
December 2022 in “Sudan Journal of Medical Sciences” This review paper discusses the effectiveness of repurposed drugs and potential novel therapies for treating COVID-19, highlighting remdesivir as the only FDA-approved medication and listing others with Emergency Use Authorization.
31 citations
,
August 1975 in “Journal of Pharmaceutical Sciences” This study found that different species metabolized minoxidil into various products, with monkeys and humans showing similar profiles primarily excreting a glucuronide conjugate, while rats and dogs showed distinct differences.