81 citations
,
September 2009 in “Birth defects research” This review discusses the mechanisms behind hair patterning during mouse embryonic development and reports no new experimental findings.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
65 citations
,
September 2004 in “The American journal of pathology” This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.
48 citations
,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified chemokine receptor ligands cxcl10 and cxcl11 as new hair-specific transcriptional targets of the Eda pathway, suggesting chemokine signaling plays a role in primary hair follicle patterning.
25 citations
,
October 2018 in “PloS one” This study explored hair follicle gene expression in Inner Mongolia Cashmere goats and identified potential regulators of the transition between growth phases, including IL17RB and ZNF genes.
14 citations
,
October 2018 in “PloS one” In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.
14 citations
,
September 2016 in “Journal of Cutaneous Pathology” This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
12 citations
,
January 2014 in “Menoufia Medical Journal” This review discusses the role of dermoscopy in diagnosing hair and scalp disorders, noting its ability to aid in differential diagnosis without the need for biopsies; it reports no new clinical results.
10 citations
,
January 2014 in “Genetics and Molecular Research” This study observed that primary hair follicles in Liaoning Cashmere goats had broader hair bulb widths compared to secondary follicles, with the difference diminishing during the anagen phase of hair follicle development.
9 citations
,
July 2020 in “Journal of Animal Physiology and Animal Nutrition” This study found that maternal melatonin supplementation improved fur quality in Rex rabbit offspring by increasing hair follicle density and altering melatonin receptor gene expression in several organs.
8 citations
,
September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
5 citations
,
July 1999 in “Plastic and Reconstructive Surgery” This study found that reparative surgical techniques significantly improved the appearance of patients dissatisfied with previous hair restoration procedures, with minor and correctable complications.
4 citations
,
April 2000 in “Plastic and Reconstructive Surgery” The document suggests fixing common hair transplant issues by combining artistic principles with plug reduction, recycling, and additional micrograft transplantation, while also potentially using arnica to help with post-operative swelling.
1 citations
,
January 2024 in “International journal of molecular sciences” This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.
1 citations
,
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
1 citations
,
April 2010 in “Expert Review of Dermatology” This review discusses primary cicatricial alopecias, detailing their classification, pathogenesis, clinical features, histopathologic findings, and treatment, without reporting new experimental results.
February 2026 in “Dermatology Reports” In this case study, trichoscopy was found to be a valuable non-invasive tool for diagnosing dissecting cellulitis of the scalp, enabling early detection and intervention to prevent disease progression and reduce the need for invasive procedures.
This review analyzed literature on primary cutaneous lymphomas involving the scalp, finding that scalp involvement in these cases often leads to non-scarring focal alopecia and may indicate more aggressive disease.
December 2013 in “Research Portal (King's College London)” This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.
December 2012 in “Drugs & Therapy Perspectives” Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.
62 citations
,
December 1994 in “Journal of Endocrinology/Journal of endocrinology” In this study, administrating ovine prolactin accelerated secondary hair follicle reactivation and moulting in cashmere goats, while bromocriptine delayed these processes.
48 citations
,
February 2010 in “Molecular biology reports” This study found that KAP7.1 and KAP8.2 genes were significantly more expressed in secondary hair follicles than primary follicles, suggesting their role in regulating cashmere fiber diameter.
32 citations
,
February 2002 in “Veterinary Dermatology” This study reported that canine dermal papilla cells showed a distinct growth pattern and strong collagen IV and laminin staining compared to dermal fibroblasts.
30 citations
,
February 2023 in “Animals” This study suggests that the period from birth to 6 months is optimal for regulating secondary hair follicle development in cashmere goats, with specific growth factors potentially playing a regulatory role.
18 citations
,
November 2016 in “Transgenic research” This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.
18 citations
,
September 2011 in “Livestock science” This study found that maternal Nano-Se supplementation in cashmere goats improved antioxidant status and promoted secondary hair follicle development in fetuses at 110 days.
4 citations
,
October 2020 in “Animal Bioscience” This study concluded that using a can containing beans as environmental enrichment for Rex rabbits improved their growth performance, carcass traits, meat quality, and hair follicle development compared to other enrichment materials or no enrichment.
4 citations
,
January 2013 in “Genetics and Molecular Research” This study found that VEGF expression and microvessel density in hair follicles of Liaoning cashmere goats follow a bimodal pattern correlated with hair development throughout the year.
August 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study characterizes the secondary hair follicles in the Lanyu pig, an indigenous breed sharing similarities with human vellus hair follicles, suggesting its relevance as a model for researching hair follicle-mediated skin regeneration and enhancing translation to human wound healing.
August 2026 in “Animal Genetics” In this study, researchers analyzed hair follicle development in Yongqing Rex rabbits, finding dynamic changes in fur thickness, coat density, and hair structure across 1 to 6 months, along with fluctuations in follicle density and gene expression linked to hair growth and quality.