18 citations
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March 2004 in “The Journal of Urology” In this study, researchers used a hypospadiac rat model to demonstrate abnormal genital development, similar to human penoscrotal hypospadias, highlighting the model's value for studying penile growth and differentiation.
8 citations
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December 2008 in “Journal of The American Academy of Dermatology” This case report describes the first known instance of fixed drug eruption linked to finasteride, confirmed through an oral challenge test that reproduced symptoms at the same skin site.
22 citations
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November 2020 in “International Journal of Environmental Research and Public Health” This study found that hidradenitis suppurativa significantly impacts patients' sexuality, with many experiencing fear of rejection, perceived unattractiveness, and negative effects on relationships and sexual activity.
May 2024 in “Reactions weekly” 6 citations
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September 2011 in “Journal of the American Academy of Dermatology” This report describes a case of secondary syphilis with an unusual folliculocentric papular eruption in an HIV-positive patient, underlining the diagnostic challenges and importance of biopsy with treponemal staining in such cases.
6 citations
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June 2014 in “PubMed” This study concluded that transurethral seminal vesiculoscopy combined with finasteride is a safe and effective treatment for recurrent hemospermia in the observed patients.
April 2026 in “BMC Oral Health” In this case report, a 45-year-old male developed recurrent, painful oral ulcers after starting finasteride for hair loss, with symptoms resolving after stopping the drug and returning upon rechallenge, suggesting a probable causal link.
3 citations
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February 2024 in “Wound Repair and Regeneration” In this systematic review, researchers examined the occurrence and treatment of penile keloids and found that circumcision is a common trigger, particularly in prepubescent children. Despite various therapeutic approaches, penile keloids are rare, complicating further study of this condition.
2 citations
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November 2019 in “BMC urology” This study used micro-CT to visualize preputial vessel distribution in a congenital hypospadias rat model, revealing that vessels at the preputial junction with good circulation were well-suited for vascular pedicle flaps in surgery.
25 citations
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August 2022 in “Frontiers in Reproductive Health” This review discusses the use of platelet-rich plasma injections for treating erectile dysfunction, noting the potential for regenerative medicine to reverse or halt disease progression, but it reports no new clinical results.
16 citations
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December 2006 in “Chinese Medical Journal” This case report describes a 12-year-old boy with congenital insensitivity to pain with anhidrosis and progressing acro-osteolysis, highlighting the severe complications and the necessity for early intervention.
March 2016 in “Reactions Weekly” Post-finasteride syndrome causes various symptoms in men using finasteride, with no known cure.
November 2022 in “American Journal of Clinical Pathology” In this case study, concurrent prostatic adenocarcinoma and a rare solitary fibrous tumor were identified on a transurethral resection of the prostate specimen.
August 2024 in “Postgraduate Medical Journal” A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.
4 citations
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December 2014 in “PubMed” This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.
8 citations
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August 2021 in “Fertility and Sterility” This review discusses the potential risks of ejaculatory dysfunction associated with both medical and surgical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and their implications for male fertility, but it reports no new clinical results.
1 citations
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June 2008 in “The Journal of Urology” This letter to the editor references a study on using dihydrotestosterone gel before hypospadias surgery but itself contains no new findings.
1 citations
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January 2014 in “Health Renaissance” This report describes a rare case of pseudopelade of Brocq in a 20-year-old male, emphasizing its unique presentation with scalp hair loss and mild itching.
September 2019 in “Research Square (Research Square)” In this study, micro-CT analysis revealed that severe hypospadias in finasteride-induced rats was associated with varying levels of preputial blood circulation, impacting potential surgical approaches.
69 citations
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July 2015 in “Pharmacotherapy” This study found that low-dose finasteride use in young men was associated with higher reporting of persistent sexual dysfunction, with some cases linked to suicidal ideation.
37 citations
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March 2005 in “Journal of Paediatrics and Child Health” This case report and review discuss hair-thread tourniquet syndrome in a 14-year-old autistic child, highlighting its rarity and the misconception of it being linked to abuse or socio-cultural practices.
3 citations
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February 2019 in “Molecular genetics and metabolism” This study found that coadministration of tadalafil and finasteride improved lower urinary tract symptoms and erectile function in men with benign prostatic hyperplasia better than finasteride alone over 26 weeks.
1 citations
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July 2024 in “Indian Journal of Sexually Transmitted Diseases and AIDS” In this study, a 38-year-old male with syphilis-related mixed pattern alopecia showed marked hair regrowth and resolution of postauricular lymphadenopathy after treatment with benzathine penicillin, suggesting that lymph node and hair examinations, along with trichoscopy, can aid in the diagnosis of alopecia syphilitica.
April 2017 in “The journal of sexual medicine” This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.
April 2024 in “International journal of research in dermatology” In this report, researchers document a rare case of a 16-year-old female on azathioprine presenting with both anagen effluvium and plica neuropathica, highlighting a unique instance of overlapping hair conditions potentially linked to medication use.
1 citations
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July 2020 in “Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya” This case report describes a patient with HIV who experienced overlapping symptoms of primary and secondary syphilis and showed clinical and serological improvement after treatment with benzathine penicillin and antiretroviral drugs.
13 citations
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January 2019 in “Endocrine journal” This study found that transdermal DHT treatment increased penile length in boys with 5α-reductase type 2 deficiency, but post-pubertal growth was limited and carried potential prostate complications.
This case report details a 17-year-old boy diagnosed with atypical juvenile pityriasis rubra pilaris (type 5) after presenting with persistent itchy skin lesions since age seven.
11 citations
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January 2018 in “Asian Journal of Andrology” Researchers observed that dutasteride and finasteride caused structural changes in the penises of both control and hypertensive rats, with dutasteride having a more pronounced effect on the corpus cavernosum.
10 citations
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December 2008 in “Journal of Clinical Neuromuscular Disease” This report describes a case where a man developed reversible myalgia and significant hyperCKemia after long-term finasteride use for male frontal baldness, with symptoms resolving upon discontinuation.