Atypical Juvenile Pityriasis Rubra Pilaris: A Case Report of Early Onset With Late Diagnosis

October 2022 in “ Cureus ”

Bakr A Albrakati, Ibrahim A Alshareef, Waseem Alhawsawi, Khalid Al Hawsawi

pityriasis rubra pilaris PRP hyperkeratosis lymphocytic infiltrates isotretinoin CARD14 mutations Accutane

TLDR A rare skin condition in a 17-year-old was diagnosed late, stressing the need for careful evaluation and genetic testing.

This case report detailed a 17-year-old boy with atypical juvenile pityriasis rubra pilaris (PRP) type 5, a rare inflammatory skin condition, which was diagnosed late despite symptoms starting at age 7. The disease, characterized by itchy, photoaggravated skin lesions covering the entire body, was confirmed through a skin biopsy showing hyperkeratosis and lymphocytic infiltrates. Treatment involved isotretinoin and regular monitoring. PRP type 5 is often misdiagnosed, highlighting the need for thorough clinical and pathological evaluation, and genetic testing for CARD14 mutations is advised due to possible familial connections.

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research Atypical Juvenile Pityriasis Rubra Pilaris: A Case Report of Early Onset With Late Diagnosis

October 2022 in “Cureus”

A rare skin condition in a 17-year-old was diagnosed late, stressing the need for careful evaluation and genetic testing.