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This article covers discussions from the Society of Urologic Oncology Annual Meeting outlining that new therapies, such as Provenge, Prostvac, and denosumab, are making the treatment of advanced prostate cancer more complex but may offer extended survival benefits.

This review discusses the potential causes and treatments for alopecia in nonhuman primates, emphasizing the need for comprehensive testing before attributing hair loss to stress.

This case report described a young Himalayan kitten in Indonesia with notoedric mange, treated successfully with topical selamectin and sarolaner, highlighting the importance of early diagnosis and management to prevent reinfestation, especially in urban areas.

In this study, pregnant spotted hyenas treated with flutamide and finasteride had lower concentrations of several sex hormones, including testosterone and luteinizing hormone, compared to untreated controls.

In this study, researchers analyzed data from Spain to find that alopecia areata is more prevalent in adults, with a point prevalence of 0.44% in 2021; they also noted significant healthcare costs and comorbidities, highlighting an unmet treatment need given limited systemic treatment use.

This study found that ringtailed lemurs consuming leucaena in Berenty absorb mimosine, which causes alopecia without affecting body condition or organ toxicity; this may increase infant mortality due to alopecic mothers.

This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.

This review systematically evaluates 13 animal and 2 mathematical models for alopecia areata, assessing their effectiveness in understanding the condition's pathogenesis and aiding in the development of new therapeutic strategies.

This study found that the estrous cycle influences the effect of the δ-GABAAR agonist THIP in reducing binge drinking behavior in female mice, with receptor expression elevated during diestrus.

This paper reviews the advancements and applications of single-cell transcriptomics in animal research, highlighting its potential to enhance understanding of animal nutrition, health, genetics, and disease models.

This report from SRUC VS highlighted a suspected case of Schmallenberg virus infection in a calf born to an imported heifer, noting consistent clinical signs and seroconversion in the dam.

This study found that essential fatty acid deficiency in rabbits leads to significant degeneration of gonadal tissue, possibly due to impaired anterior pituitary gland function.

This study found hair regrowth in the majority of AA-affected mice and rats treated with diphencyprone, suggesting its potential utility for understanding human alopecia areata and the drug's therapeutic action.

This study found that higher dihydrotestosterone (DHT) levels are associated with reduced crowing complexity in Kokok Balenggek roosters.

The measures for eyebrow and eyelash hair loss in severe Alopecia Areata are reliable and useful for clinical trials.

In this study, overexpressing TSPO in the mouse hippocampal dentate gyrus led to significant anxiolytic and antidepressant-like effects, partly through increased allopregnanolone biosynthesis.

This study found that androgen binding in male rat livers involves specific androgen receptors, which decrease with castration and are inducible in female livers with testosterone.

This research aims to address gaps in understanding alopecia areata by evaluating the real-world effectiveness and safety of baricitinib, identifying predictors of therapeutic response, and exploring the long-term impact on life quality, including sexual health. Results are not reported in the abstract.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

This animal study observed that treatment with the S1PR modulator NXC736 significantly reduced lesion area and CD8+ T cell infiltration in mice with alopecia areata, suggesting its potential as a promising therapy for the condition.

In this report, the researchers described a follicular dysplastic syndrome in two adult white-tailed deer, where gross alopecia and histologic signs suggestive of alopecia areata were observed, potentially predisposing affected deer to environmental exposure.

This study compared JAK inhibitors for moderate-to-severe alopecia areata and found brepocitinib 30mg and deuruxolitinib 12mg to be most effective, though deuruxolitinib may cause more adverse events. Further research is needed for long-term efficacy and safety.

Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.

This study found that exposure to certain pesticides may be associated with delayed sexual maturation in adolescent males.

Zinc deficiency in monkeys causes skin issues and reproductive problems, but supplementation reverses these effects.

This study found significant species differences in the enzyme activity and inhibitor affinities of prostatic 5α-reductases from rats, dogs, and humans, with variable potencies for different 3-oxo-4-azasteroid inhibitors across species.

This paper highlights advances in Developmental Dynamics, noting how epoa-deficient zebrafish can model Diamond-Blackfan anemia like disorders for drug screening, Alx4 mouse models offer insights into craniofacial development, and mTORC1 signaling is crucial for retinal development.

This study suggests that the Grasp protein may play a role in regulating skin homeostasis following UVB exposure by influencing p53-mediated apoptotic responses in mice.

This study suggests that biopsies can play a significant role in diagnosing and managing difficult cases of alopecia by identifying pattern mimics and overlaps, which are more common than previously realized.