51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” This review examines androgen replacement therapy in women for treating androgen deficiency symptoms and reports no new clinical results, while noting potential safety within a specific dose range.
49 citations
,
February 2009 in “Maturitas” This review discusses the use of testosterone therapy for low libido in women, noting mixed evidence on breast cancer risk and a lack of long-term safety data.
37 citations
,
September 2018 in “The Journal of Clinical Endocrinology and Metabolism” This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.
30 citations
,
March 2010 in “European Journal of Dermatology” This article discusses hair loss in postmenopausal women as often being multifactorial, reviewing various conditions affecting this group, but reports no new research findings.
28 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” This review examines age-related changes in androgen levels in women and explores the rationale for testosterone replacement therapy, but it reports no new clinical findings.
26 citations
,
January 2013 in “BioMed Research International” This review discusses the hormonal influences on hair cycling disorders in post-partum and postmenopausal women and notes the lack of evidence for effective targeted treatments.
23 citations
,
April 2021 in “Journal of Clinical Medicine” This review compiles existing data on frontal fibrosing alopecia and highlights the promise of 5-alpha reductase inhibitors as a treatment option, while noting the need for clarity on its cause and progression.
18 citations
,
June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
17 citations
,
April 2006 in “Dermatologic Clinics” This review discusses common skin disorders in older women and their treatments, but it reports no new clinical results.
14 citations
,
January 2015 in “Current problems in dermatology” This review addresses treatment approaches for female pattern hair loss, highlighting that combining different therapies may be more effective than single treatments, but no new results are reported.
13 citations
,
December 2020 in “Dermatologic Therapy” This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.
11 citations
,
August 2019 in “The Journal of Sexual Medicine” This study found that women with nonclassic congenital adrenal hyperplasia (NC-CAH) reported lower sexual function and higher sexual distress compared to those with classic CAH (C-CAH), particularly among those showing signs of androgen excess.
10 citations
,
December 2002 in “International Journal of Dermatology” This case study reports a 66-year-old woman developing shortness of breath while taking 50 mg/day of cyproterone acetate for androgenetic alopecia, a complication not previously documented in women with this condition.
8 citations
,
February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
6 citations
,
September 1998 in “The Journal of The British Menopause Society” This review discusses the changes in androgen levels with age in women and the potential benefits of testosterone replacement therapy as part of hormone replacement therapy for postmenopausal women, but it reports no new clinical results.
5 citations
,
January 2017 in “Dermato-endocrinology” This study found that postmenopausal women with a history of hirsutism and/or oligo-amenorrhea have a higher prevalence of several comorbidities, including heart and respiratory diseases, than those without these reproductive history markers.
4 citations
,
December 2021 in “Experimental and Therapeutic Medicine” This article describes adult female acne as a complex condition affected by genetic, hormonal, and environmental factors, with hormonal therapies highlighted as particularly valuable for treatment.
4 citations
,
July 2021 in “Journal of Dermatological Treatment” This meta-analysis reported that finasteride 1 mg/day significantly increased hair count in male androgenetic alopecia compared to placebo, but highlighted persistent sexual side effects and associated depression risk.
2 citations
,
January 2018 in “Biology and medicine” In this study, researchers observed that a significant number of women in Eket, Nigeria, have low testosterone levels, while a subset with high free testosterone may have polycystic ovary syndrome.
2 citations
,
June 2017 in “Journal of The American Academy of Dermatology” This article discusses the uncertainty regarding distinct skin findings and cardiometabolic profiles among PCOS subtypes and reports no new clinical data.
2 citations
,
September 2007 in “International Journal of Impotence Research” This case study reports that low-dose testosterone therapy improved libido and sexual functions in a 36-year-old fragile X carrier female with hypoactive sexual desire disorder when monitored regularly for lab parameters.
1 citations
,
June 2021 in “Revista de la Facultad de Ciencias Médicas de Córdoba” This case report describes a postmenopausal woman with virilization linked to ovarian stromal hyperthecosis, highlighting the importance of detailed clinical evaluation and complementary testing for accurate diagnosis and treatment.
1 citations
,
October 2008 in “Expert Review of Dermatology” This review discusses frontal fibrosing alopecia, noting its frequent misdiagnosis and highlighting the need for larger studies to better understand its epidemiology, causes, and treatment options; it reports no new clinical findings.
This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.
December 2025 in “International Journal of Research in Dermatology” This consensus highlights that addressing nutritional and endocrine deficiencies through lifestyle modifications, nutritional support, and medical interventions is crucial for managing hair loss associated with endocrine and gynecological disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, nutritionists, endocrinologists, and gynecologists.
August 2025 in “Frontiers in Endocrinology” This study examined postmenopausal hyperandrogenism related to ovarian disease and found that specific biochemical markers can help differentiate between tumorous and non-tumorous cases, with a good level of sensitivity and specificity, supporting surgical intervention for resolution.
In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.
January 2025 in “JCEM Case Reports” Among postmenopausal women, this case study observed that a rare ovarian tumor called thecoma, found via MRI, was associated with high testosterone levels and symptoms of mild virilization such as hirsutism, indicating surgery as the primary treatment.
November 2017 in “Elsevier eBooks” This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.
July 2015 in “Cambridge University Press eBooks” Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.