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Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Plant-based ingredients are effective and safe for modern skincare products.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Minoxidil effectively treats female pattern hair loss.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.

Type I interferons play a key role in the development of various skin diseases.

In Brazil in 2018, the most common skin issues were acne, photoaging, and nonmelanoma skin cancer, with treatments often including topical medications and sunscreen.

Mice without certain skin proteins had abnormal skin and hair development.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.

The Cross-section Trichometer is a new tool that can measure hair quantity and detect hair loss and growth.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.