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Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.

MED1 affects skin wound healing differently in young and old mice.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.

Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Adding fetal calf serum helps Merkel cells survive and change shape.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

Mange in rabbits is a serious disease that can spread to humans and is treated with medications and supportive care.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Using iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles increases drug release but reduces its targeting to hair follicles.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Eating flaxseed made rabbit hair longer and thicker and improved their weight and blood sugar and cholesterol levels.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Polymeric nanoparticles show promise for treating skin diseases.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.