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Chitosan-decorated carriers may improve topical finasteride delivery for hair loss treatment.

This study found that both acute and chronic exposure to nano polystyrene in laboratory rats disrupted hematological function, increased oxidative stress, and led to behavioral and physiological changes, like anemia-like effects and neurological disruptions, suggesting its potential as a cumulative toxicant.

This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.

This study found that human hair keratin coatings enhanced adhesion and proliferation of L929 mouse fibroblasts compared to uncoated and collagen type 1 surfaces, suggesting keratin's potential as a surface coating for cell cultures.

This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.

This study found that incorporating a block copolymer significantly alters the size and morphology of niosome drug delivery systems made of non-ionic surfactants and cholesterol, affecting their stability.

PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.

This study reported that a modified nanoprecipitation protocol can effectively create PLA nanoparticles capable of delivering compounds into hair follicles, with promising potential for hair follicle therapy and cosmetic applications.

In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.

This study found that novel biodegradable nanocarriers with highly hydrophobic cores significantly increased the solubility and sustained release of hydrophobic drugs and dyes, showing promise for drug delivery applications.

This study found that bio-based waterborne polyurethanes derived from castor oil may offer effective hair-styling performance without skin irritation and appear to be safer for the environment compared to traditional hair sprays.

The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.

This study reports that optimized PLA nanoparticles can effectively target hair follicles to deliver both lipophilic and hydrophilic compounds, suggesting potential applications in hair cosmetics and treatments.

This study found that cefazolin-loaded silica nanoparticles embedded in polycaprolactone nanofibers successfully inhibited Staphylococcus aureus growth while maintaining stem cell viability, suggesting their potential use in wound healing.

This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.

This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.

In this study, researchers found that nanomaterials designed for plastic surgery applications show promising results, including a 95% dynamic wrinkle filling rate and enhanced hair density by 41%; however, challenges like potential long-term safety issues and high production costs must be addressed.

PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.

In an animal study, this research explored the use of a self-therapeutic nanoparticle for treating psoriasis in mice, finding that it could prevent and treat psoriatic symptoms as effectively as standard therapies without causing side effects like hair loss and skin wrinkling.

This study found that clindamycin-loaded PHA nanoparticles showed potent antibacterial effects against MRSA and enhanced wound healing in a mouse model of MRSA-infected wounds, indicating their potential as a novel treatment for these infections.

The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.

This study found that freeze-dried finasteride nanoparticles significantly improved the dissolution rate and pharmacokinetic parameters compared to pure drug formulations, suggesting enhanced stability and solubility for poorly water-soluble drugs.

This study reports that delivering alopecia medications like minoxidil, finasteride, and spirinolactone via polymeric nanoparticles may improve their effectiveness by enhancing drug delivery to hair follicles, especially in cases where hair loss is linked to stress and immune changes post-COVID-19 infection.

This study found that dexamethasone-loaded polymeric nanoparticles, particularly those combining ethyl cellulose with Eudragit® RS, may improve controlled release and penetration of corticosteroids into the skin and hair follicles compared to traditional methods.

This study observed that smaller polymeric submicron particles provided more efficient selective drug delivery to inflamed skin in a mouse model, enhancing therapeutic effects while reducing systemic adverse effects.

This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

In this study, researchers found that silica nanoparticles synthesized using cold plasma showed a higher biofilm inhibition effect on Staphylococcus aureus and Escherichia coli compared to those made with a magnetic stirrer.

This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.