10 citations
,
November 2016 in “Clinical and experimental dermatology” This case report describes a 52-year-old woman with multiple autoimmune conditions suggesting a diagnosis of PAS IIIC, characterized by prominent skin-related symptoms.
9 citations
,
February 2012 in “Clinical Neurology and Neurosurgery” In this paper, three APS patients were followed over time, showing that the diagnosis and course of autoimmune polyglandular syndrome can evolve, highlighting the need for careful monitoring and potential re-evaluation.
2 citations
,
January 2016 in “Gynecological Endocrinology” This case report describes a patient with polyglandular autoimmune syndrome type 2 diagnosed via adrenal crisis, with thyroid, adrenal, and ovarian involvement.
1 citations
,
January 2022 This case report describes a 29-year-old woman diagnosed with both systemic lupus erythematosus and Graves' disease, illustrating the occurrence of autoimmune polyendocrine syndromes with specific combinations of autoimmune disorders.
April 2024 in “Research Square (Research Square)” This case report describes a 27-year-old male with autoimmune polyglandular syndrome type 1, characterized by symptoms including fever, dysarthria, dysphagia, oral candidiasis, nail dystrophy, alopecia, hypoparathyroidism, and dilated cardiomyopathy. The study highlights unique bilateral symmetrical brain calcifications and underscores the syndrome’s diverse manifestations.
62 citations
,
January 2010 in “Hormone research in paediatrics” This study found that the R257X mutation in the AIRE gene is prevalent among Russian patients with autoimmune polyglandular syndrome type 1, particularly in those with hypoparathyroidism and chronic mucocutaneous candidiasis.
10 citations
,
April 2003 in “Clinical neurology and neurosurgery” This case study reports a 33-year-old man with autoimmune thyroiditis and alopecia universalis experiencing reversible CNS demyelination, possibly due to autoimmune activity against CNS antigens.
9 citations
,
January 2007 in “Gynecological Endocrinology” This case report presents the first known instance of combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2 in a patient, exploring potential mechanisms for their interrelation.
8 citations
,
June 2012 in “Journal of Crohn s and Colitis” This case report documents a 33-year-old male with autoimmune polyglandular syndrome type 2, including diabetes mellitus type 1, Hashimoto thyroiditis, adrenal insufficiency, and Crohn's disease, highlighting the ongoing difficulties in managing multiple autoimmune conditions.
5 citations
,
February 2015 in “Endocrinology Diabetes and Metabolism Case Reports” This case report describes a patient with autoimmune polyglandular syndrome type 3 who experienced total hair regrowth following the successful control of diabetes with insulin therapy.
2 citations
,
January 2021 in “Case reports in endocrinology” In this case report, a girl with autoimmune polyglandular syndrome type 1 experienced stabilized disease and reversal of alopecia universalis after treatment with glucocorticoids and methotrexate.
2 citations
,
December 2020 in “Endocrinology, diabetes & metabolism case reports” This case study highlights the complexity of managing autoimmune polyglandular syndrome type 1, emphasizing the need for thorough clinical history, high suspicion for early diagnosis, and continuous long-term follow-up.
June 2025 in “International Medical Case Reports Journal” This case study reported on a 30-year-old male with autoimmune polyglandular syndrome type 2, highlighting rare co-occurrence with alopecia universalis and emphasizing the importance of recognizing non-endocrine symptoms for early diagnosis and management of autoimmune endocrinopathies.
This case study describes a 29-year-old woman diagnosed with both systemic lupus erythematosus and Graves' disease, illustrating a specific combination of autoimmune conditions within Autoimmune Polyendocrine Syndromes.
January 2019 in “Przegląd Dermatologiczny” This report presents a case of a 57-year-old woman with APS-4, generalized alopecia, and rheumatoid arthritis, emphasizing the need to screen for other autoimmune disorders in patients with a single organ-specific autoimmune disease.
4 citations
,
January 2010 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study described the clinical course of six young patients with type 1 autoimmune polyglandular failure, all of whom initially presented with hypoparathyroidism followed by mucocutaneous candidiasis and adrenal failure.
33 citations
,
October 2018 in “BMJ Case Reports” This case report describes a 6-year-old who developed autoimmune conditions including type III polyglandular autoimmune syndrome following drug-induced hypersensitivity syndrome, prompting an investigation into associated triggering factors.
December 2020 in “Rev. Amazon.” This study identified that 80% of a rural population in Ecuador uses medicinal plants like Aloe vera for treating hair conditions, highlighting the prevalence of ancestral plant knowledge.
3 citations
,
December 2016 in “KSBB Journal” This study found that a herbal medicine increased hair growth in a mouse model, showing strong antioxidant activity and similar 5-alpha-reductase inhibition to finasteride without cytotoxicity in human dermal papilla cells.
46 citations
,
July 1988 in “Journal of The American Academy of Dermatology” This review discusses various skin lesions associated with endocrinologic disorders such as Cushing's syndrome and adrenal insufficiency, and it reports no new clinical results.
8 citations
,
January 2008 in “European Journal of Pediatrics” This report describes two prepubertal children with autoimmune gastritis, highlighting the need to screen paediatric patients with organ-specific autoimmune diseases for co-existing conditions.
31 citations
,
May 2021 in “Journal of endocrinological investigation” This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.
March 2012 in “Journal of the American Academy of Dermatology” Treating ovarian-related inflammation may help hair regrowth in women with alopecia areata.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
86 citations
,
October 2017 in “Translational pediatrics” This review discusses how ophthalmic findings can reveal key endocrine disorders and reports no new clinical results, emphasizing the eye's role in diagnosing and managing systemic diseases like diabetes and Graves' ophthalmopathy.
79 citations
,
March 2017 in “Dermatologic clinics” This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.
20 citations
,
September 2005 in “Clinics in Dermatology” This review discusses the skin manifestations of metabolic diseases like diabetes and gout, emphasizing their role in diagnosis and monitoring, but it presents no new research findings.
18 citations
,
August 2012 in “Cutaneous and Ocular Toxicology” This study found that alopecia areata patients had increased insulin resistance compared to controls, suggesting a potential link between inflammation, stress axis activation, and insulin resistance in this population.
13 citations
,
January 2013 in “International Journal of Trichology” This study found that androgenetic alopecia patients showed significantly higher perifollicular lymphocytic inflammation and fibrosis compared to controls, emphasizing the need for histopathological evaluation during hair transplantation.
11 citations
,
July 2012 in “Current Opinion in Pediatrics” This review discusses dermatologic signs in childhood endocrine disorders and highlights their importance in early diagnosis and treatment, but it reports no new clinical findings.