This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
12 citations
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January 2019 in “Journal of Endocrinology” In this study, baicalin from Scutellaria baicalensis decreased androgen levels in both cells and PCOS model rats by inhibiting key gene expression, suggesting it may be a potential treatment for hyperandrogenism in PCOS.
1 citations
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February 2025 in “Journal of Pharma Insights and Research.” This analysis explores the potential benefits of various nutraceuticals, such as Ashwagandha, Cinnamon, and Fenugreek, in managing Polycystic Ovarian Disease, suggesting these may improve menstrual regularity, insulin sensitivity, and other symptoms when used alongside conventional treatments.
This study identified ISPP-Rb, a novel immuno-stimulatory complex from Royoporus badius, that significantly activates murine macrophage cells and induces multiple proinflammatory cytokines.
22 citations
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August 2020 in “Molecules” This study found that applying AGN root extract containing decursin to mouse skin accelerated hair growth and altered inflammatory cytokine levels compared to a control.
28 citations
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May 2019 in “Life Sciences” This study found that ginsenoside Rb1 promoted the growth of mink hair follicles and dermal papilla cells, potentially through activating the PI3K/AKT/GSK-3β signaling pathway.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the dual nature of Abrus precatorius as both a traditional medicine and a toxin, emphasizing its rich phytochemical profile and potential therapeutic applications, while noting the need for rigorous quality control and clinical trials to ensure safety and efficacy.
3 citations
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January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
May 2022 in “Journal of pharmacognosy and phytochemistry” This study carried out a detailed pharmacognostic and phytochemical analysis of Sphagneticola calendulacea leaves, which may help authenticate this plant used in treating inflammation and alopecia.
21 citations
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June 2022 in “Molecules” This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.
2 citations
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May 2023 in “Life” This review summarizes the mechanisms by which Plumbagin, a naphthoquinone derived from plants, may impact inflammation and explores its potential biological effects, highlighting areas that require further comprehensive research before considering it for therapeutic use.
5 citations
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January 2024 in “Advances in Pharmacological and Pharmaceutical Sciences” This review explored the biological properties of Punica granatum, noting its antioxidant, anti-inflammatory, and antimicrobial activities, and highlighted its potential as a therapeutic agent for various conditions; however, more extensive clinical trials are needed to confirm its effectiveness and safety.
61 citations
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September 2010 in “Fitoterapia” This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
25 citations
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January 2013 in “Journal of Industrial and Engineering Chemistry” This study found that cubosomal suspensions significantly enhanced the hair growth-promoting effects of Thuja orientalis, Polygonum multiflorum Thunberg, and Espinosilla extracts in a mouse model, making them as effective as Minoxidil.
August 2026 in “Pharmacological Research - Modern Chinese Medicine” In this study, topical applications of Agrimonia pilosa extract and agrimonolide demonstrated notable anti-inflammatory and wound healing benefits in animal models, significantly reducing inflammation and enhancing wound closure compared to controls. However, further research in humans is needed to confirm these preclinical findings.
July 2024 in “Fitoterapia” This study found that Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose improved androgenetic alopecia symptoms in mice by reducing DHT levels and activating specific hair growth pathways.
34 citations
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August 2011 in “Journal of Natural Medicines” This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.
This study reviews the pharmacological potential of Bacopa monniera, highlighting its extensive therapeutic effects such as antioxidant, anti-inflammatory, and memory enhancement properties, which are primarily attributed to its diverse bioactive compounds.
January 2026 in “Industrial Crops and Products” In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviews the traditional and emerging medicinal uses of Clitoria ternatea Linn., highlighting its extensive chemical composition and potential health benefits, but notes the lack of human trial evidence and the need for better testing methods to ensure consistent quality and efficacy.
This article explores whether Melampus, a mythological healer, may have intentionally caused the madness of Proetus' daughters through the use of herbs, despite being credited with their cure.
September 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.
March 2023 in “Chemical biology & drug design” This study found that 8% Panax notoginseng saponins may promote hair follicle growth in C57BL/6J mice, potentially through the Wnt/β-catenin signaling pathway.
2 citations
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February 2019 in “JOJ dermatology & cosmetics” The study found that Anagen grow, a herbal serum, promotes hair growth elongation and may inhibit the alpha reductase enzyme, suggesting it as a safe, effective alternative to finasteride and beneficial alongside minoxidil for reducing scalp dryness.
This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
May 2026 in “Quality in Sport” This study suggests that berberine may offer multiple benefits for women with polycystic ovary syndrome by improving metabolic and hormonal profiles, though further research is needed on its long-term effects on reproductive outcomes.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, in silico analysis identified Saponin Re and Emodin as promising candidates for topical treatment of androgenetic alopecia, with Biochanin A having the most favorable safety profile among the tested compounds.
5 citations
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April 2022 in “Evidence-based Complementary and Alternative Medicine” This study explored the mechanism of Shaoyao Gancao decoction in treating alopecia areata and found that it may be closely related to the PI3K/AKT signaling pathway.