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This study concluded that using human umbilical cord blood mononuclear cells transfected with VEGF and FGF2 genes enhances skin wound healing in rats, demonstrating greater wound revascularization compared to controls.

This study found that inducing hair follicles into the anagen stage by plucking significantly enhances antibody responses in mice after topical DNA vaccine application, compared to retinoic acid or TPA treatments.

This study found that topically delivering KGF-1 DNA plasmid increased epithelial thickness and skin strength, suggesting potential benefits for strengthening compromised skin.

This review explores biomaterials in non-viral gene delivery systems and highlights the need for more research to better understand how various parameters affect gene delivery processes, without reporting new experimental results.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

This study found that inducing hair follicles into the anagen-onset stage in mice enhances the immune response to a topically applied DNA vaccine against anthrax.

This research explores developing liposomal formulations to enhance the delivery of difficult-to-absorb agents directly to hair follicles and sebaceous glands, with minoxidil and plasmid DNA as study molecules.

This study found that retinoic acid pre-treatment enhanced the efficiency of gene transfer into mouse skin for potential therapeutic applications.

In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.

This research reports that the ultra-high sulfur keratin promoter acts as a tissue-specific promoter in mouse hair follicles, as shown by induced expression of GFP and β-gal in that region post-transfection.

This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.

This article describes standard methods for studying DNA methylation dynamics in mouse skin and hair follicle stem cells but presents no new research findings.

This study reports that the completeness of DNA degradation in hair during cornification varies among individuals and affects the success rates of forensic hair DNA analysis.

This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.

This study found that androgen/androgen receptor signaling accelerates premature senescence in dermal papilla cells, highlighting a potential target for treating androgenetic alopecia.

This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.

This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.

This study found that minicircle-based gene therapy significantly lowered total homocysteine levels and improved liver CBS activity in a mouse model of CBS deficiency.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

This study reported that during wheat polyploidization, decreased DNA methylation and specific hypomethylated promoters were associated with altered gene transcription, contributing to root hair elongation and improved nitrate uptake, highlighting the role of epigenetic regulation in enhancing crop traits.

This study found that polyamines enhance genome integrity by facilitating homologous recombination-mediated DNA repair, suggesting a novel role for polyamines beyond promoting cell growth and proliferation.

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

This review provides an overview of azelaic acid's dermatological uses, mechanisms, and its potential in skin cancer treatment, but reports no new clinical results.

This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.

This article reviews androgen insensitivity syndrome and highlights the factors contributing to phenotypic diversity in 46,XY patients with AR gene mutations, reporting no new clinical results.

This review discusses AR-modulating agents developed between 2012 and 2018, highlighting challenges with ligand-binding domain antagonists and proposing nonconventional approaches targeting other domains as promising strategies.

This study suggests that impaired VDR signaling in mice leads to dysregulated Ddit4 expression, impacting hair cycle progression and wound healing.

This study found that DNA methylation may regulate the differential expression of the BMP7 gene in Hu sheep lamb skin of different patterns, and it influences the proliferation and cell cycle of dermal papilla cells, with demethylation treatment increasing BMP7 expression and cell proliferation.

This study found that lncRNA2919 negatively impacts hair follicle regeneration by decreasing follicle depth and density in a rabbit model, suggesting a regulatory role in the hair follicle cycle through DNA methylation.

This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.