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Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Finasteride may lower cholesterol and slow heart disease progression.

Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.