156 citations,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
147 citations,
April 1994 in “Drug Safety” Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
76 citations,
June 2008 in “Journal of the American Academy of Dermatology” The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.
56 citations,
January 2021 in “Clinical and Experimental Medicine” The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
40 citations,
July 2017 in “Frontiers in Medicine” Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
22 citations,
June 1980 in “International Journal of Dermatology” The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
17 citations,
June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
14 citations,
June 2014 in “Journal of Pharmaceutical Sciences” Formulation P-08-016 better targets hair follicles for baldness treatment.
9 citations,
April 2023 in “Frontiers in immunology” New technologies help us better understand how skin microbes affect skin diseases.
9 citations,
January 2015 in “Laboratory Animal Research” Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.
4 citations,
July 2014 in “International Journal of Dermatology” Twins had rare skin cysts likely due to genetics.
3 citations,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
1 citations,
July 2018 in “Elsevier eBooks” Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.
1 citations,
October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
January 2018 in “Springer eBooks” The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
87 citations,
March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
78 citations,
October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
52 citations,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
40 citations,
January 1996 in “Journal of Dermatological Treatment” Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.
38 citations,
December 2011 in “British Journal of Dermatology” Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.
26 citations,
August 2018 in “American Journal of Clinical Dermatology” Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.