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Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

Turing patterns are now recognized as important in developmental biology.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Muscles and nerves that cause goosebumps also help control hair growth.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Skin problems are very common in people with end-stage kidney disease.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.