April 2026 in “Frontiers in Pharmacology” This study suggests that nanotechnology-based drug delivery systems can improve the targeted, sustained delivery and stability of dermatological treatments, potentially leading to better outcomes and reduced side effects for various aesthetic skin conditions, though further clinical trials are needed to confirm these benefits.
8 citations
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November 2020 in “Journal of Cosmetic Dermatology” This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.
8 citations
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May 2024 in “Advanced NanoBiomed Research” This review examines advancements in lipid and inorganic nanocarriers, such as liposomes and inorganic nanoparticles, for transdermal drug delivery, noting enhanced absorption and stability but acknowledging that few have reached clinical use.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights Croton tiglium's dual therapeutic and toxic properties, noting its potential for hair growth promotion through PKC-mediated pathways, while emphasizing the challenges posed by its toxicity for safe clinical use.
July 2025 in “International Journal of Pharmacy and Pharmaceutical Science” This review explores the scientific basis and formulation strategies of herbal shampoos, highlighting the therapeutic benefits of bioactive plant extracts and discussing challenges and future directions for their development in the cosmetic industry.
March 2026 in “Skin Appendage Disorders” This narrative review highlights the distinct needs of pediatric hair care, emphasizing gentler formulations due to differences in children's hair physiology, structure, and barrier function, and calls for targeted regulations and research due to limited safety evidence.
1 citations
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July 2025 in “The Open Dermatology Journal” This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.
September 2026 in “Cureus” In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.
August 2023 in “Skin Research and Technology” In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.
15 citations
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January 2021 in “Cellular and Molecular Biology” This study found that Prosopis farcta is a rich source of phenolic compounds with strong antioxidant activity, suggesting its potential for use in food, beverage, feed, and pharmaceutical applications.
1 citations
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January 2022 in “Journal of Pharmaceutical Sciences” This study developed a stable, cosmetically appealing formulation for the topical delivery of the peptide FOL-005, enhancing skin permeation and maintaining stability by keeping the peptide solid and in a water-free environment with particle sizes under 10 µm.
1 citations
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October 2021 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This study highlights that improving medical professionals' knowledge of hair cosmetics can enhance patient adherence to alopecia treatments and reduce health risks from incorrect use of hair products.
17 citations
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August 2010 in “International Journal of Cosmetic Science” This study found that a cosmetic formula containing 2% Orthosiphon stamineus leaf extract significantly reduced skin oiliness and pore size, showing better results than a formula with 1% zinc gluconate.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
January 2015 in “CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION)” This study developed a rapid and reliable ultra high performance liquid chromatography method for analyzing 17 key ingredients in hair growth cosmetics.
4 citations
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August 2025 in “Molecules” This study highlights the potential of medicinal plants like Rubus vulgaris and Plantago major as sources for skin disorder treatments due to their bioactive compounds' antioxidant, anti-inflammatory, and antimicrobial effects.
March 2026 in “Preprints.org” This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.
January 2006 in “FarFar - Pharmacy Repository” This paper reviews cosmetic active substances for treating pregnancy-related skin changes like hyperpigmentation and striae, discussing their efficacy and safety but reports no new clinical results.
183 citations
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January 2018 in “Cosmetics” This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.
November 2023 in “Journal of the American Academy of Dermatology” This study explored spontaneous repigmentation after phenol-croton oil peels in skin of color, finding that temporary hypopigmentation resolved by day 21 in both a black-skin domestic pig model and human clinical observations, highlighting potential for these procedures despite past concerns about pigmentation issues.
January 2018 in “Journal of Islamic Research and Studies” In this study, a 39-year-old male with mild seborrheic dermatitis followed an individualized phytotherapy program, including hair massages with jojoba and patchouli oils, herbal rinses, and weekly masks, which showed positive effects in reducing dandruff after completion.
34 citations
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September 1992 in “Journal of the American Academy of Dermatology” This article provides dermatology residents with essential information on cosmetic use to help manage skin conditions and reactions, without reporting new clinical results.
May 2021 in “Research journal of topical and cosmetic sciences” In this study, oral supplementation of Microcore’s TrichovitalsTM significantly improved the appearance of facial skin, hair, and nails over 12 weeks in healthy middle-aged adults compared to a control group.
September 2025 in “Biochemical and Cellular Archives/Biochemical and cellular archives” This study evaluated herbal hair care products, including oils, shampoos, and dyes, formulated with ingredients like coconut oil and neem, and found they potentially offer safe and environmentally friendly alternatives to synthetic products with nourishing and antimicrobial properties.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The researchers reported that a coconut oil-based polyherbal hair oil developed using traditional medicinal plants demonstrated satisfactory physicochemical properties, including stability and pH suitability for scalp application, though further biological evaluation is needed to confirm therapeutic effects.
January 2026 in “Eng—Advances in Engineering” This study developed a biodegradable nonwoven textile using a starch-based biopolymer and fruit extracts, resulting in materials that are stronger, more hydrophilic, and capable of releasing beneficial compounds over 72 hours, positioning them for potential use in medical, healthcare, and cosmetic applications.
298 citations
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June 2019 in “Marine Drugs” This review discusses the properties and bioextraction methods of chitin and chitosans, emphasizing their potential use in eco-friendly cosmetic manufacturing and reports no new experimental findings.
January 2026 in “Journal of Materials Chemistry B” In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.
3 citations
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October 2018 in “Фармацевтичний часопис” This study examined the use of emulsifiers and preservatives in soft emulsion-type drugs, suggesting that biogenic surfactants could be promising alternatives to synthetic agents that often cause side effects.
This study examined the use of plant extracts as natural hair dye colourants, highlighting their antioxidant properties and eco-friendly benefits. The authors reported that plant-based dyes effectively deliver vibrant colours and enhance hair health while offering a sustainable alternative to synthetic dyes.