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Minoxidil can cause skin irritation like eczema and rash in some users.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

Finasteride affects young male rats' brain function and behavior negatively.

Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.

New tests detect finasteride and dutasteride in urine quickly and easily.

The compound 4c showed strong potential as an anticancer agent.

Using a video otoscope effectively treated ear infections in dogs.

Fluridil promotes hair growth safely and effectively for androgenetic alopecia.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

Using a stimulating cream shampoo before applying Minoxidil helps it penetrate hair follicles better, enhancing its hair growth-promoting effect.

Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.