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5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

A family was found with both Trichorhinophalangeal syndrome and Loose Anagen Syndrome, suggesting a genetic connection.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Targeting colon cancer stem cells might lead to better treatment results.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.