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This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.

This study found that the TYK2 inhibitor deucravacitinib did not significantly improve hair regrowth in patients with alopecia areata compared to placebo, suggesting it may not be effective for this condition. No new safety issues were identified.

The trial is ongoing, but researchers are evaluating the efficacy and safety of REZPEG, a potential new therapy for severe alopecia areata, which selectively expands regulatory T cells.

This study found that administering testosterone increased the expression of sexual behavior and elevated serum testosterone and DHT levels in female capuchin monkeys, hinting at potential insights into testosterone use and its risks in humans.

In this study, researchers found that Derinat treatment in mice maintained the hair cycle in the anagen phase and reduced TRPCs-mediated intracellular ROS accumulation, potentially improving hair growth by altering the skin microenvironment.

This technical report from the European Food Safety Authority responds to comments on its previous scientific opinion regarding a health claim about spermidine and hair growth, reporting no new experimental results.

The topical finasteride spray was safe and well-tolerated with stable effects.

This study reported that topical BPM31543 was safe and well-tolerated for patients on taxane-based chemotherapy, with some efficacy indicated in reducing hair loss at all dosages tested.

This study examined the effects of constant-release melatonin on the SOX21 gene in Inner Mongolia Cashmere goats, finding that it stabilized gene expression and reduced stress responses with notable expression changes except in March, April, and May.

This study found that in both rodents and humans, knee laxity increased at certain phases of the reproductive cycle due to sex-steroid influence, particularly under high levels of estrogen and progesterone.

In this study, researchers found that changes in Wnt signaling pathways play a crucial role in feather follicle morphogenesis during chicken embryo development.

This study found that oral JAK3 and TYK2/JAK1 inhibitors improved clinical outcomes in alopecia areata patients by reducing immune responses and enhancing hair keratin expression, with stronger effects in those with shorter disease duration.

This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.

This study found that bimatoprost eye drops significantly increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits within one month.

This study discovered that key genes like KAP3-1 and KRTAPs are closely linked to the growth cycle of cashmere in Inner Mongolian goats, identifying March as the primary cycle's onset.

This study found that PRP injections may safely improve penile curvature and PDQ scores in men with stable-phase Peyronie's Disease, although the curvature reduction observed was not enough to determine long-term clinical significance.

Clascoterone safely promotes hair growth similar to minoxidil.

In this study, once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution both promoted hair regrowth in women with female pattern hair loss, but noninferiority of the foam was not established.

This study found that nonobese women with idiopathic hirsutism exhibited lower nitrite/nitrate concentrations and higher fibrinogen levels compared to control subjects, but these were similar to levels in women with polycystic ovary syndrome.

This study reported that HSP27 protein shows varied expression in human scalp hair follicles across anagen, catagen, and telogen stages, suggesting a role in hair follicle biology.

This study found that a cell therapy product, RCS-01, was well tolerated in aged skin and led to significant increases in gene expression related to extracellular matrix homeostasis, although the small cohort size limited further efficacy analysis.

Among men with androgenetic alopecia, this study found that taking 5 mg of KX-826 twice daily significantly increased hair count compared to a placebo, with the treatment being well-tolerated and no serious adverse effects reported.

Once-daily 5% minoxidil foam increases hair regrowth and density in women with hair loss, but not as effectively as twice-daily 2% minoxidil solution, though it's safer and more convenient.

This study found that tristimulus colorimetry is a sensitive and quantitative method for projecting hair growth rates in depilated mice, and it observed that 890 nm LED irradiation promotes hair regrowth.

Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.

This study found that myristoleic acid promotes dermal papilla cell proliferation and anagen signaling through autophagy, cell cycle progression, and activation of the Wnt/β-catenin and ERK pathways.

In this study, EC chemotherapy was found to be noninferior to TC in causing grade 3 or 4 neutropenia among HR+/HER2-negative breast cancer patients, but EC was associated with more other adverse events.

Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.

This study observed that osteopontin mRNA levels in rat hair follicles vary throughout the hair cycle, peaking during the catagen phase and disappearing in the telogen and anagen phases.

This abstract does not provide specific findings or results.