Search

everythinglearnresearchcommunity

for

Search:↓

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Prolactin slows down hair growth in mice.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Micrografts improve hair density and thickness without side effects.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Finasteride doesn't affect hormone levels in normal men.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Applying certain inhibitors to the skin can promote hair growth without harming cells.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.