8 citations,
January 2016 in “Indian Journal of Pharmacology” Finasteride and dutasteride can cause severe, lasting side effects.
6 citations,
September 2002 in “Acta pædiatrica” A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and inhaled budesonide.
2 citations,
July 2022 in “Frontiers in Cardiovascular Medicine” Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.
1 citations,
August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
1 citations,
December 2018 in “International Journal of Current Microbiology and Applied Sciences” Bitter Apple has various medicinal uses, including treating tumors, skin conditions, ulcers, asthma, jaundice, and rheumatism.
1 citations,
October 2017 in “The Journal of Urology” Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.
August 2024 in “Quality in Sport” Lifestyle changes like diet and exercise are crucial for managing PCOS.
March 2024 in “Current materials science” Fisetin, found in fruits and vegetables, may help treat various health conditions like inflammation, diabetes, heart issues, cancer, and hair loss.
November 2023 in “International journal of biology, pharmacy and allied sciences” Banana plants have many health benefits, but more research is needed to confirm them.
June 2023 in “Pharmaceuticals” Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.
119 citations,
June 2021 in “Heliyon” The review on Glycyrrhiza glabra, commonly known as licorice, highlighted its diverse phytochemical constituents, including glycyrrhizin and glycyrrhizic acid, which exhibited various pharmacological activities. These compounds were noted for their anti-cancer, anti-inflammatory, anti-microbial, and antispasmodic properties, among others. Additionally, licorice showed potential health benefits such as stimulating hair growth, controlling obesity, and providing hepatoprotective and memory-enhancing effects. The review also addressed the side effects and toxicity associated with licorice and its bioactive components.
30 citations,
July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
17 citations,
April 2015 in “Tropical Journal of Pharmaceutical Research” Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
9 citations,
May 2017 in “Universal journal of pharmaceutical research” Glycyrrhiza glabra has various medicinal properties, including antibacterial and antioxidant effects.
4 citations,
July 1987 in “Laboratory Animals” The study used hairless Sprague Dawley rats to assess the ability of retinoids to inhibit epidermal ornithine decarboxylase activity induced by sellotape stripping. A total of 100 rats (50 males and 50 females) aged 4 to 11 weeks were examined to validate the model. The study found that hair growth occurred at 6-7 weeks and 10-11 weeks, with more pronounced growth in males. No histological changes were observed in the stratum corneum, but an increase in epidermal thickness was noted in 9-week-old males. Sellotape stripping was more effective and consistent in females, with lower individual variation (5%-10% in females vs. 10%-20% in males). The research concluded that female rats aged about 8 weeks provided the most reproducible response and ease of use for this model.
3 citations,
January 2022 in “International Research Journal of Ayurveda & Yoga” Psoralea corylifolia (Bakuchi) is effective for treating various health issues, especially skin disorders.
July 2002 in “Journal of Cosmetic Dermatology” The document discussed the effectiveness of modern physical and pharmacological methods for unwanted hair removal, highlighting laser technology and pharmacological treatments like Eflornithine. Laser treatments, using selective photothermolysis, targeted pigmented hair bulbs, causing thermal damage and resulting in thinner, softer regrowth, with effects lasting around 8 months after an average of 2 sessions. Eflornithine, a topical cream, reduced hair growth by at least 50% over prolonged use by blocking an enzyme essential for hair shaft synthesis. These methods were more effective than traditional mechanical and chemical hair removal techniques.
125 citations,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
85 citations,
March 2012 in “Revista Brasileira de Farmacognosia” The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.
6 citations,
October 2020 in “medRxiv (Cold Spring Harbor Laboratory)” Early treatment improved COVID-19 outcomes, and spironolactone helped reduce risks in females with high androgen levels.
May 2024 in “Scientific African” Three natural compounds from Ghanaian plants may help treat BPH and alopecia.
June 2023 in “Current Issues in Molecular Biology” DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.
January 2023 in “Eurasian journal of science and engineering” Medicinal plants in Kurdistan have potential health benefits and need more research for drug development.
July 2002 in “Journal of cosmetic dermatology” Hair loss can be treated with medications like finasteride and surgical methods like hair transplants.
7 citations,
January 2022 in “Anais Da Academia Brasileira De Ciencias” Essential oils from Hedychium spicatum have potential for developing natural drugs with pain-blocking, fever-reducing, anti-inflammatory, and antioxidant properties.
7 citations,
January 2020 in “Journal of Dermatology” Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.
2 citations,
January 2019 in “Asian journal of pharmaceutical and clinical research” Amla is a natural remedy with many health benefits, including antiviral and antibacterial properties.
1 citations,
December 2023 in “Egyptian Journal of Veterinary Science” Astragalus polysaccharides nanogel heals wounds better than Gold-Silver nanocomposite gel.
1 citations,
February 2023 in “Drug Design Development and Therapy” Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
September 2024 in “Ain Shams Medical Journal” Androgenic alopecia causes hair thinning, and treatments include minoxidil, finasteride, and light therapy.