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300-330 / 1000+ resultsresearch Finasteride: the first 5 alpha-reductase inhibitor.
![Forsythiasides: A review of the pharmacological effects](/images/research/762bfb47-5caa-4a51-911a-12a13cd7c753/small/16909.jpg)
research Forsythiasides: A review of the pharmacological effects
Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.
![Medical management of benign prostatic hyperplasia](/images/research/21173d96-67ed-492e-a03f-d2128a41a0e2/small/36743.jpg)
research Medical management of benign prostatic hyperplasia
Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.
research Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design
![Sex-Related Differences in the Pharmacological Response in SARS-CoV-2 Infection, Dyslipidemia, and Diabetes Mellitus: A Narrative Review](/images/research/643c584d-a3c0-442c-a851-a5cf68d756dd/small/16592.jpg)
research Sex-Related Differences in the Pharmacological Response in SARS-CoV-2 Infection, Dyslipidemia, and Diabetes Mellitus: A Narrative Review
Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.
research Patient‐Level Adverse Event Patterns in a Single‐Institution Study of the Multi‐Kinase Inhibitor Sorafenib
Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
![Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends](/images/research/beb8ad37-7424-4cd0-be0d-d9e96fdf67f9/small/13125.jpg)
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
![Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines](/images/research/e85d07a7-ede4-4b83-a49d-be1b6a6dcfe3/small/11538.jpg)
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
![Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study](/images/research/4df7041b-dea0-4e29-8ea9-127869f4069c/small/20565.jpg)
research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
![Hair Growth Effect of DN106212 in C57BL/6 Mouse and Its Network Pharmacological Mechanism of Action](/images/research/654375e7-a32c-4b4e-9687-6f0563ee083e/small/15727.jpg)
research Hair Growth Effect of DN106212 in C57BL/6 Mouse and Its Network Pharmacological Mechanism of Action
DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.
![A Systematic Review On Traditional Use, Phytochemical And Pharmacological Properties Of Some Medicinal Plants Growing In Kurdistan Region – Iraq](/images/research/3a81faed-386f-4e1a-9f82-705a04b3fe6e/small/20650.jpg)
research A Systematic Review On Traditional Use, Phytochemical And Pharmacological Properties Of Some Medicinal Plants Growing In Kurdistan Region – Iraq
Medicinal plants in Kurdistan have potential health benefits and need more research for drug development.
![Comparative study on eucalyptol and camphor rich essential oils from rhizomes of Hedychium spicatum Sm. and their pharmacological, antioxidant and antifungal activities](/images/research/62843ddd-0308-4508-95ce-dd82e89fc996/small/22830.jpg)
research Comparative study on eucalyptol and camphor rich essential oils from rhizomes of Hedychium spicatum Sm. and their pharmacological, antioxidant and antifungal activities
Essential oils from Hedychium spicatum have potential for developing natural drugs with pain-blocking, fever-reducing, anti-inflammatory, and antioxidant properties.
![Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms](/images/research/2e07abf6-267b-48f5-a529-fd49965eae38/small/16709.jpg)
research Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms
Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
research Fissistigma oldhamii (Hemsl.) Merr.: Ethnomedicinal, Phytochemistry, and Pharmacological Aspects
Fissistigma oldhamii has compounds that help with pain, inflammation, and other health issues.
![Angelica Sinensis and Chinese Arborvitae: A Review on its Phytochemical & Pharmacological Importance](/images/research/6a28c4b7-de37-473e-bcbf-745facbd3fc4/small/26742.jpg)
research Angelica Sinensis and Chinese Arborvitae: A Review on its Phytochemical & Pharmacological Importance
Angelica Sinensis and Chinese Arborvitae have various medicinal benefits, including anti-inflammatory and anti-cancer effects.
![Genus Thuja: A comprehensive review on botany, traditional uses, pharmacological activities and phytochemistry](/images/research/cdf42650-89df-4b43-bedb-751a3e449053/small/36357.jpg)
research Genus Thuja: A comprehensive review on botany, traditional uses, pharmacological activities and phytochemistry
Thuja plants have medicinal properties and potential for developing new therapies.
![A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology](/images/research/2869e89e-cb7a-41e7-b7ba-4a3e01f92575/small/22774.jpg)
research A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology
Hibiscus rosa-sinensis is used in traditional medicine and is safe in high doses, with various health benefits.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
![Pathobiology of chemotherapy-induced hair loss](/images/research/1ca54ac4-a496-436b-a149-c7735db7c8a6/small/25939.jpg)
research Pathobiology of chemotherapy-induced hair loss
Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
![Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in the<i>Arabidopsis</i>Root](/images/research/ca17c633-4bc6-4bcf-8865-9c9c3cb9caf1/small/21959.jpg)
research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in theArabidopsisRoot
Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.
![Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination](/images/research/b9b4f216-6c69-4b6a-9db3-89137d8ef259/small/15103.jpg)
research Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination
The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
![Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia](/images/research/3295f2b3-632b-4cfb-96ec-9343a84216bd/small/17482.jpg)
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
![Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration](/images/research/e7022d15-8e4e-4407-8b3f-74aa2fdb6890/small/2808.jpg)
research Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
![Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress](/images/research/91428354-f9e8-4775-9dfb-dbb43f20cacf/small/14294.jpg)
research Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress
A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
![Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia](/images/research/f8c40e2f-1ed6-41a2-aeed-aa4682dcce13/small/15223.jpg)
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
![Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?](/images/research/26f2a146-02cd-4322-8e1e-fe89f8990985/small/12454.jpg)
research Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?
Topical minoxidil improves hair loss in 80% of women with breast cancer undergoing endocrine therapy.
![Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes](/images/research/c7c6269c-096c-4495-a954-6ffab4ccd99b/small/15586.jpg)
research Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes
Researchers made two new compounds that could be used for medicine.
![The Effect of Topical Minoxidil Pretreatment on Nonsurgical Delay of Rat Cutaneous Flaps: Further Studies](/images/research/0127ff5d-1bc0-4759-b556-ca4af33375e0/small/14464.jpg)
research The Effect of Topical Minoxidil Pretreatment on Nonsurgical Delay of Rat Cutaneous Flaps: Further Studies
Minoxidil improved rat skin flap survival but was less effective than surgical methods.
![Present Chemotherapy Induced Alopecia and Research in Future](/images/research/56509169-38bd-493f-bf9f-6fe9d9b9fdf7/small/34542.jpg)
research Present Chemotherapy Induced Alopecia and Research in Future
Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.