77 citations
,
July 2012 in “Journal of Investigative Dermatology” The researchers observed that overexpression of Wnt10b in a mouse model can induce hair follicle regeneration by switching follicles from the resting phase to the growth phase via the Wnt-β-catenin signaling pathway.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.
17 citations
,
December 2010 in “Journal of Investigative Dermatology” This study found that higher levels of the protein Flii were associated with enhanced hair follicle regeneration and longer hair fibers in a mouse model.
May 2014 in “Journal of Investigative Dermatology” This article reviews recent imaging and genetic tool advances that enable in vivo study of hair regeneration and assessment of skin parameters, but it reports no new clinical results.
7 citations
,
January 2019 in “Journal of clinical medicine research” This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.
1 citations
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October 2022 in “Current Dermatology Reports” This review discusses various skin reactions after SARS-CoV-2 infection and COVID-19 vaccination, noting a higher incidence with mRNA vaccines than adenovirus vector vaccines, and reports no new clinical results.
August 2024 in “Cosmetics” This review highlights caffeine's diverse benefits in cosmetics and nutricosmetics, noting its antioxidant properties, ability to treat skin disorders like androgenic alopecia, and potential to enhance sunscreen effectiveness, though penetration into deeper skin layers remains challenging.
February 2025 in “Processes” This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” This study found that knocking down P-cadherin expression in cultured human hair follicles recreates the hair abnormalities seen in patients with hypotrichosis with juvenile macular dystrophy.
1 citations
,
March 2015 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This study developed and validated a precise RP-HPLC method for simultaneously estimating minoxidil and aminexil in pharmaceutical formulations with good accuracy and specificity.
22 citations
,
August 2013 in “PLOS ONE” This study found that using a non-invasive multielectrode array for gene electrotransfer in hairless guinea pigs increased gene expression in the epidermis significantly, with minimal skin changes observed.
18 citations
,
April 2013 in “PLOS ONE” This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.
February 2024 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.
1 citations
,
January 2009 in “Elsevier eBooks” This chapter reviews techniques for treating pseudofolliculitis barbae and suggests that combining daily shaving with topical treatments like glycolic acid may effectively manage this condition without new clinical results reported.
32 citations
,
July 1999 in “Fertility and Sterility” This study found that both finasteride and flutamide effectively reduced hirsutism, with flutamide being more effective than finasteride in decreasing hirsutism scores and hair diameter over 12 months.
12 citations
,
December 2002 in “Fertility and Sterility” In this study, a combination of spironolactone and finasteride was found to significantly improve hirsutism scores without increasing side effects compared to spironolactone alone.
108 citations
,
January 2003 in “Fertility and Sterility” This study found that flutamide at 250 mg daily modestly improved hair thinning in premenopausal women with hyperandrogenic alopecia over one year, while cyproterone acetate and finasteride were not effective.
37 citations
,
April 2002 in “The American Journal of Medicine” St. John's Wort can cause dangerous high blood pressure if taken with certain foods.
21 citations
,
September 2004 in “Fertility and Sterility” Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.
6 citations
,
January 2016 in “Annals of Dermatology” This study found that glycosaminoglycan levels were higher in the occipital area of the hair shaft compared to the parietal area, with children showing higher levels than adults.
1 citations
,
June 2023 in “International Journal of Pharmaceutical Sciences and Medicine” This review found that Sansevieria trifasciata contains numerous chemical compounds and has been traditionally used to treat various ailments, with prior studies confirming its pharmacological activities such as anti-ulcer, antibacterial, antioxidant, antidiabetic, and anticancer effects, among others.
March 2026 in “International Journal of Homoeopathic Sciences” This study reported a case where individualized homeopathic treatment notably reduced hair fall and promoted hair regrowth over nine months in a 40-year-old man with androgenic alopecia, while also improving his confidence and body image.
February 2026 in “Bioimpacts” This review discusses advancements and challenges in using 3D bioprinting for diabetic foot ulcer treatments, highlighting potential improvements and existing limitations in replicating skin architecture and clinical application.
January 2026 in “International Journal of Current Research and Review” This review of Adiantum capillus-veneris highlights its traditional medicinal uses, rich phytochemical profile, and broad range of pharmacological activities, but emphasizes the need for more research to validate and expand its therapeutic applications.
April 2025 in “International Journal of Homoeopathic Sciences” This case report describes marked improvement in symptoms for a 24-year-old woman with PCOS following individualized homeopathic treatment, which reportedly included a reduction in irregular menstruation, vaginal discomfort, and weight gain.
December 2024 in “International Ayurvedic Medical Journal” This study observed that Ayurvedic treatments using Gandmala Kandan Rasa, Kanchanar Guggulu, and Varunadi Kwath provided symptomatic relief and reduced thyroid-stimulating hormone levels in a 35-year-old female patient with hypothyroidism over a 90-day period.
July 2024 in “International Journal of Pharmaceutical Sciences and Medicine” This review highlights that Nyctanthes arbor-tristis contains numerous phytochemicals and has traditional uses for various conditions. It also reports pharmacological activities, suggesting potential benefits for diabetes, cancer, inflammation, and more.
January 2024 in “International journal of Indian medicine” In this article, the authors aimed to educate readers on common hair disorders linked to improper care, emphasizing prevention and treatment using Ayurvedic principles such as Dincharya and yoga.
October 2023 in “Cognizance journal” This study explores using agent-based modeling and nutrition science to predict and treat oral and dental diseases as alternatives to traditional incarceration for managing criminal behavior, but results are not reported.
July 2023 in “International Ayurvedic medical journal” In this single case study, Ayurvedic treatments using Madhuka taila nasya and Japaakusumadi lepa were reported to benefit a patient with premature hair graying, suggesting a potential safe and effective alternative to conventional methods.