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In this study, researchers found that unexplained liver damage in PCOS patients may involve iron metabolism and the miR-761-hepcidin/GPX4 axis, suggesting potential therapeutic targets.

In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.

This study found that cPPARγ and dnPPARγ isoforms are differentially expressed in healthy human skin, suggesting that PPARγ modulators may have compartment-specific effects depending on isoform presence.

In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.

In this study, the stability properties of various active pharmaceutical ingredients (APIs) were characterized, revealing how factors like pressure and water sensitivity influence their intrinsic stability and potential degradation.

This study used a newly developed RP-HPLC method to accurately measure finasteride distribution in human cadaver skin after applying different vesicular drug delivery systems.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This article discusses the role of external beam radiotherapy as a primary treatment method for cancer and reports no new clinical findings.

In this study, combining deferasirox with sorafenib significantly reduced liver fibrosis and preneoplastic lesions in rats while also lessening adverse effects compared to sorafenib alone.

Povidone-iodine nail solution effectively treats nail infections caused by chemotherapy.

In this study, researchers identified a temperature-sensitive mutation in the FERONIA gene of plants that prevents root hair formation at elevated temperatures, highlighting its role in maintaining root hair growth and response to plant hormones.

This study found that the presence of benzeneseleninic acid in commercial anhydride samples lowered the reaction rate during the oxidation of a finasteride intermediate compared to pure anhydride.

This study found that treating cats infested with Lynxacarus radovskyi using Fipronil resulted in complete resolution of the infestation by day 15.

In this study, the researchers aimed to evaluate the levels of substance P, folic acid, and ferritin in the serum of female patients experiencing hair fall and trichodynia.

This study found that using 1,4-butylenediamine bismaleimide for hair perming through thiol-Michael click chemistry offers comparable efficiency to conventional oxidative methods, with enhanced durability and reduced damage to hair fibres, preserving mechanical, color, and surface properties.

Entadfi, a mix of finasteride and tadalafil, is used for BPH.

This review examines the development and challenges of using PROTACs, a targeted protein degradation strategy, to treat cancer by degrading specific proteins like PARPs and GPX4, highlighting issues such as target diversification and bioavailability.

This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.

In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.

This report describes a case where a woman with frontal fibrosing alopecia initially presented with symptoms resembling rosacea, but further investigation led to a diagnosis of FFA, resulting in a treatment change to oral finasteride and hydroxychloroquine.

This study found that phosphorus limitation in Chaetophorales strains led to enhanced hair formation and increased phosphatase activity, suggesting a significant relationship between phosphorus status and morphology.

In this study, BPA rapidly increased dendritic spine and synapse densities in cultured rat hippocampal neurons, with involvement of estrogen receptors and ERK1/2 and p38 pathways, but disrupted dihydrotestosterone's effects on synaptic plasticity.

This study found that a new analytical approach revealed an increased brain pregnenolone level following finasteride treatment in a mouse model, suggesting potential for improved understanding of neurosteroid roles in brain excitability.

This study highlights the ZmNF-YC1-ZmAPRG pathway as a potential mechanism to improve maize tolerance to phosphorus deficiency, emphasizing its role in modulating lipid and photosynthetic activity, although direct impacts on root adaptations remain unclear (Bai et al., 2024).

This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.

This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.

This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.

In this study, a topical formulation with compounds from the monoterpenoid family significantly improved hair growth indicators like anagen:telogen ratio, hair fall, and visual hair density in men and women with pattern hair loss.

This study found that three sessions of injectable platelet-rich fibrin (i-PRF+) significantly improved hair follicle density, hair volume, and thickness, as well as patient satisfaction in women with female pattern hair loss, with only minor self-limited adverse effects reported.