April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
April 2012 in “Informa Healthcare eBooks” Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.
February 2011 in “Journal of the American Academy of Dermatology” A 60-year-old man with a long-term balding condition also developed a rare hair loss condition usually seen in postmenopausal women.
June 2003 in “Obstetrical & Gynecological Survey” Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
December 2020 in “Galen Medical Journal” Alopecia patients have more mast cells in their scalps, especially in severe cases and older age, with alopecia areata showing the highest increase.
March 2023 in “Chinese Journal of Dermatology” Protecting hair and scalp from sunlight may help prevent hair loss.
Dermoscopic features can help distinguish female androgenetic alopecia from telogen effluvium and healthy controls.
April 2022 in “Journal of advances in medicine and medical research” Topical minoxidil 5% effectively improves hair density and width in men with androgenetic alopecia.
February 2022 in “Chinese Journal of Dermatology” A 36-year-old woman with worsening hair loss over 10 years was treated with various medications, and after six months, her hair loss did not worsen significantly.
October 2021 in “QJM: An International Journal of Medicine” ADSC injections improve hair density, thickness, and reduce inflammation in female pattern hair loss.
November 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Inflammation plays a key role in male and female pattern hair loss, and focusing on this could help develop better treatments.
June 2020 in “Journal of Drugs in Dermatology” Frontal fibrosing alopecia can be misdiagnosed as androgenetic alopecia in African American women.
December 2015 in “Journal of skin and stem cell” Using a gel called Diclofenac can potentially cause hair to grow back in bald spots in older men.
February 2009 in “Journal of The American Academy of Dermatology” Female hair loss can be diagnosed using specific trichoscopy criteria.
3 citations,
June 2017 in “Medical lasers” A treatment combining laser energy and injections improved hair loss and unexpectedly also reduced hair graying.
1 citations,
December 2018 in “Journal of Pakistan Association of Dermatology” Dermoscopy is useful for diagnosing different types of hair loss.
1 citations,
November 2017 in “International Journal of Research in Medical Sciences” Dermoscopy helps distinguish between scarring and non-scarring hair loss and accurately diagnoses hair and scalp conditions without needing hair plucking.
October 2021 in “Technology transfer: innovative solutions in medicine” The combined treatment improved scalp health in women with early-stage hair loss.
September 2014 in “Chinese Journal of Dermatology” Hair diameter difference, brown skin discoloration around hair follicles, and missing hair in certain areas are key signs of androgenetic alopecia (commonly known as hair loss) when viewed under a dermoscope.
3 citations,
January 2019 in “Skin Research and Technology” Frequent use of hair straighteners can cause hair loss similar to scarring alopecia in young Turkish women.
July 2022 in “Journal of Investigative Dermatology” Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.
39 citations,
March 2017 in “Dermatologic clinics” UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
December 2020 in “Pathology” A man's skin condition and poor diet led to a scurvy diagnosis.
Cryotherapy is the best depigmentation method for vitiligo but needs an expert to perform it.
December 2005 in “Journal of the American Academy of Physician Assistants” The woman was diagnosed with lichen planopilaris and can be treated with corticosteroids.
July 1974 in “Archives of Dermatology” Ultraviolet light treatment with trioxsalen was ineffective for vitiligo in the cases described.
178 citations,
December 2011 in “Journal of Dermatological Case Reports” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.
26 citations,
January 1992 in “Carcinogenesis” The study investigated the effects of multiple exposures to 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein, and ethyl phenylpropriolate (EPP) on murine epidermal cells, focusing on the induction of ornithine decarboxylase (ODC) activity. While single applications of these agents caused similar hyperplasia and ODC induction, multiple treatments revealed significant differences in ODC activity, with TPA and mezerein inducing more than EPP. Immunocytochemical analysis showed distinct patterns of ODC-positive cells, with TPA prominently affecting perifollicular cells, mezerein affecting both interfollicular and perifollicular areas, and EPP affecting only interfollicular cells. Flow cytometry identified three keratinocyte subpopulations, with TPA causing the expansion of an intermediate-sized subpopulation not seen with EPP or mezerein. The findings suggested that TPA, a potent tumor promoter, selectively expanded a keratinocyte subpopulation hyperinducible for ODC, potentially important for neoplastic transformation, while mezerein and EPP were less effective in this regard.
16 citations,
April 2007 in “Journal of Medical Primatology” The monkey's hair loss was due to an autoimmune disease, not genetics.