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The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.

Rats had lasting erectile problems after stopping a certain medication.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Finasteride is considered the best treatment for hair loss, despite side effects.

Gene differences affect finasteride side effects in men with hair loss.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Post-finasteride syndrome's existence is uncertain; more research needed.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Testosterone is crucial for development, growth, and various body functions in mammals.

Finasteride side effects in young men may be linked to specific gene variations.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Finasteride for hair loss may cause erectile dysfunction due to tissue fibrosis, and various factors contribute to female sexual dysfunction.

Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.