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Pioglitazone may help treat lichen planopilaris, but more research is needed.

This study reviewed in vivo studies and clinical trials on phenolic compounds, like tannins and flavonoids, for treating hair loss, noting their antioxidant and anti-inflammatory effects but highlighting the need for more clinical trials to confirm benefits.

This cross-meta-analysis examined policosanol biorefining methods in 18 Ibero-American countries, reporting that Cuba, Spain, Brazil, Chile, Mexico, and Portugal show significant advances, but highlighted the need for better coordination between academia and industry for improved yield efficiency.

This study found that a curcumin-labeled particle-associated antiseptic penetrated deeper into hair follicles in porcine skin than particles without antiseptic.

This study reports that poliosis can be an adverse effect of topical prostaglandin F2α analog therapy in patients treated for primary open angle glaucoma.

This study successfully developed a method to measure four flavonoids from Platycladus orientalis leaves in rat plasma, which was used in a pharmacokinetic study on healthy rats.

This study found that the natural alkaloid cepharanthine effectively inhibited porcine epidemic diarrhea virus infection in newborn piglets.

This study found that certain fatty acids and triterpenoid-glycosides from Eclipta prostrata L. leaves exhibit potent inhibitory effects on the protein tyrosine phosphatase 1B enzyme, suggesting potential anti-diabetic and anti-obesity benefits.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.

This study identified and characterized eight compounds, including furanocoumarins and pterocarpans, from the aerial parts of Bituminaria basaltica, with β-caryophyllene and germacrene D as main constituents of its essential oil.

This thesis explores the synthesis and antiproliferative properties of phenylpropanoid sucrose esters, noting the absence of synthetic methods for most of this compound class due to their structural complexity.

This study found no significant differences in hair growth between two formulas of hair tonic from meniran extract, one with a menthol enhancer, despite variations in hair length and weight measurements.

This study analyzed the ethanol extract of pacing tawar leaves and found it contains alkaloids, saponins, tannins, and steroids but not flavonoids, suggesting potential for use in natural medicinal products.

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.

In this study, a parsley-derived n-hexane fraction formulated into a coconut oil-based nanoemulsion demonstrated significant hair regrowth comparable to 3% minoxidil, with near-complete coverage by day 17, suggesting potential as a topical hair growth treatment.

This study found that Pomiferin may effectively stimulate extracellular matrix protein expression in skin and scalp models, with results comparable to retinol, suggesting potential as a topical treatment ingredient.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

In this study, researchers observed that Pectin from Nagpuri oranges significantly increased colony counts of probiotic bacteria like L. acidophilus and L. plantarum both in vitro and in vivo, suggesting potential use as a prebiotic or synbiotic in nutraceutical formulations.

In this study, aleglitazar and its metabolite M6 were evaluated for safety in non-clinical settings, revealing organ-targeting effects common to PPAR agonists but no significant tumor increase in rat carcinogenicity studies, supporting progression to Phase 3 clinical trials.

Philippine stingless bee propolis may promote hair growth and fight cancer.

This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.

In this study, the researchers found that glycerol strongly influenced the physical characteristics of an anti hair loss cream containing Saw Palmetto extract, notably improving its spreadability, viscosity, and stability without causing skin irritation.