Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers demonstrated that CD4 T cells from skin-draining lymph nodes in mice with alopecia areata can transfer the disease to recipient mice, revealing a critical role for CD4 T cells in disease development and suggesting potential therapeutic targets.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

This study found no causal relationship between obesity and androgenetic alopecia, suggesting that their previously observed link is likely due to confounding factors.

This study examined the genetic basis of alopecia areata by analyzing gene expression differences between patients and healthy controls, identifying critical pathways, hub genes, transcription factors, and miRNAs implicated in the disease, and suggesting potential targets for treatment.

This study found that most postgraduate health students had a moderate level of awareness about alopecia, with no significant difference between genders. Only 20.3% felt confident in their knowledge of the hair fall cycle's pathogenesis, highlighting the need for increased educational efforts.

This study identified pathogenic or likely pathogenic gene variants in 70.1% of Russian families affected by hypohidrotic ectodermal dysplasia, expanding knowledge of causative mutations.

This review discusses advancements in understanding the genetic and stem cell involvement in androgenetic alopecia, evaluates current treatments, and emphasizes the need for evidence-based guidelines but presents no new clinical results.

This review discusses recent advances in the understanding of androgenetic alopecia, focusing on genetic factors and new diagnostic and treatment approaches, but it does not provide new clinical results.

This study observed that individuals with alopecia areata who had the gut bacterium Enterococcus faecalis exhibited serum biomarker levels closer to healthy controls, suggesting potential benefits for hair growth and immune modulation through its immunoregulatory effects.

This review discusses advanced biomedical technologies, such as nanotechnology and stem cell-based approaches, for treating androgenetic alopecia, detailing their benefits, current applications, and challenges, without reporting new experimental results.

This study found that young adult Ukrainian men with alopecia areata had significantly different skinfold thickness at several body sites compared to healthy peers, suggesting unique patterns of fat distribution associated with the disease.

Ritlecitinib effectively treats severe Alopecia Areata by reducing harmful immune activity in the skin.

CBD can help hair grow by supporting scalp health and reducing inflammation.

In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.

This study found that patients with Alopecia Areata had significantly higher levels of the chemokines MIG and IP-10 compared to healthy controls, suggesting these molecules may serve as potential biomarkers for diagnosing and monitoring the condition.

This study observed changes in the electrical and viscoelastic properties of erythrocytes, as well as hemostatic system activation, in women with alopecia following COVID-19 infection, potentially contributing to alopecia development and informing treatment strategies.

This source did not report new findings but provided a comprehensive overview of alopecia areata in children, emphasizing progress in understanding this condition and highlighting the need for further research to improve treatment options for young patients.

This study established a standardized in-vitro 3D skin model using adult diseased skin cells to investigate the underlying mechanisms of small fiber neuropathies, providing a foundation for further research into their pathophysiology.

A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.

In this case-control study, researchers found that patients with alopecia areata had significantly higher serum levels of interleukin-18 and NLRP3 compared to healthy controls, suggesting a potential link between these inflammatory markers and the disease.

In this case study, researchers detailed two Saudi cases of the ultra-rare Trichohepatoneurodevelopmental syndrome, identifying pathogenic variants in the CCDC47 gene and reinforcing a strong gene-disease association, which helps clarify the disorder's clinical features and genetic mutations.

This review article examines the latest understanding of androgenetic alopecia's causes and treatment options, emphasizing current research on alternative treatments beyond the approved medications, finasteride and minoxidil, due to potential side effects and the psychological impact of the condition.

This study provides a comprehensive review of Ayurvedic insights into Darunaka, suggesting that its management principles can still improve quality of life by addressing underlying pathophysiology.

This study found that a dietary intervention in dogs alleviated atopic dermatitis symptoms by modulating immune responses and skin microbiome composition compared to baseline, but with similar non-significant trends when compared with a positive control diet.

In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.

This review explored treatment options for alopecia areata in the military health care system, evaluating the pathogenesis and impact of the condition as well as the efficacy and safety of FDA-approved JAK inhibitors, baricitinib and ritlecitinib.

This review discusses seborrheic alopecia in young people, its possible link to fungal infections, and suggests that Malassezia spp. flora may play a key aetiologic role.

In this study, tea tree oil was found to have substantial antibacterial activity and promote proliferation and migration of hair follicle stem cells in vitro, indicating potential benefits for treating scalp alopecia areata.

This study found that A-FABP serum levels were significantly higher in male patients with androgenetic alopecia compared to controls, and the authors concluded that A-FABP could serve as a biomarker for early detection of this condition.

This abstract discusses alopecia areata, highlighting its complex autoimmune pathogenesis involving immune cells and signaling molecules, and underscores the importance of accurate diagnosis and tailored management strategies, noting the need for further research to improve treatments.