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research Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly(ethylene-co-vinyl alcohol) membranes for hair follicle regeneration
This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
research Multiple Concurrent Pilonidal Sinuses: Case report and Literature review
In this case report, researchers described an exceptionally rare occurrence of a 19-year-old female having three concurrent pilonidal sinuses at intermammary, umbilical, and sacrococcygeal locations, with surgical and conservative treatment leading to favorable healing outcomes.
research 心音図の読み方の基礎 (心電図・心音図の価値と限界(特集))
This report presents a rare case of lichen spinulosus in a 52-year-old woman, featuring hyperkeratotic follicular papules and a dense lymphohistiocytic infiltrate in affected skin areas.
research UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS DETERMINATION OF FINASTERIDE AND TAMSULOSIN IN COMBINED DOSAGE FORM
This study developed and validated a UV spectrophotometric method for accurately measuring finasteride and tamsulosin in solutions and tablets, demonstrating good sensitivity and precision.
research Finasteride plus doxazosin combination tops in BPH
research Case report: Pseudoporphyria in a 56-year-old man as a result of finasteride intake
Finasteride may cause pseudoporphyria, a blistering skin condition.
research JAK Inhibitor Baricitinib in the Treatment of Oral Lichen Planus: A Case Report
In this case study, a patient with refractory oral lichen planus experienced marked improvement within one month of daily treatment with baricitinib, contributing to the evidence supporting the use of JAK inhibitors for lichen planus.
research Peer Review #1 of "Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway (v0.1)"
This study suggests that melatonin enhances the growth properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through its receptors in a 3D culture system.
research Penggunaan Simplex Lattice Design (SLD) dalam Optimasi HPMC dan Propilen Glikol Formula Gel Cinchonine Sebagai antibakteri Cutibacterium acnes (C.Acne)
The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
research Jenis-jenis Progestin dalam Preparat Kontrasepsi
This source highlights the role of progestin in contraception, noting that while different types have varying progesteronic potential and effects, they share similar contraceptive mechanisms, allowing tailored use based on patient conditions.
research Association between Lipid Accumulation Product and Hirsutism in Patients with Polycystic Ovary Syndrome
This study demonstrated a significant association between high lipid accumulation product (LAP) and hirsutism in women with polycystic ovary syndrome (PCOS).
research A novel PLEC nonsense homozygous mutation (c.7159G > T; p.Glu2387*) causes epidermolysis bullosa simplex with muscular dystrophy and diffuse alopecia: a case report
This paper describes a case of epidermolysis bullosa simplex with muscular dystrophy associated with a novel PLEC mutation and diffuse alopecia, highlighting a potential genetic link that remains uncertain.
research ALTERAÇÕES FACIAIS DECORRENTES DO TRATAMENTO DA MÁ OCLUSÃO DE CLASSE III, COM DEFICIÊNCIA DE MAXILA, EMPREGANDO DISJUNÇÃO MAXILAR E TRAÇÃO REVERSA
This study found significant cephalometric changes in patients with skeletal Class III malocclusion treated with rapid maxillary expansion and reverse traction, demonstrating maxilla advancement and improved facial convexity.
research Oral gabapentin for scalp pruritus in patients with lichen planopilaris: A case series
This study links scalp pruritus in lichen planopilaris and its variants to the inflammation-induced release of substance P and calcitonin gene-related peptide by sensory nerves around hair follicle inflammation sites.
research FEATURES OF THE COURSE OF LICHEN PLANOPILARIS IN MEN
This study discusses clinical cases of Lichen Planopilaris in men that were initially misdiagnosed and inadequately treated, resulting in significant irreversible hair loss.
research Direct reprogramming of human fibroblasts into hair-inducing dermal papilla cell-like cells by a single small molecule
In this study, fibroblasts treated with the small molecule peficitinib were reprogrammed into dermal papilla cell-like cells capable of inducing hair growth, offering a new strategy for hair loss treatment.
research Midwifery qualifying examination
research INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Simultaneous estimation of finasteride and tamsulosin hydrochloride by reverse phase HPLC in bulk and pharmaceutical dosage form
This investigation reports a new RP-HPLC method for accurately estimating Finasteride and Tamsulosin Hydrochloride in bulk and tablet forms, which may serve in routine pharmaceutical analysis.
research Notices
This article describes the structure and offerings of microsurgical workshops at Canniesburn Hospital, noting that no new research findings are reported.
research Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle
In this study, polymeric micelles containing retinoic acid were found to improve targeted delivery to hair follicle structures in human skin more efficiently than a marketed retinoic acid gel, suggesting potentially safer and more effective acne treatment.
research Etude de films minces et de nanoparticules obtenus par auto-assemblage de copolymères à blocs et leurs interactions avec un oligo/polysaccharide
This study suggests that polymersomes decorated with chitosan improve the transdermal delivery of finasteride, providing an alternative drug delivery system with higher drug retention in the skin.
research Preparation of novel polymeric microspheres for controlled release of finasteride
The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.
research Cell observation method under near-living conditions by scanning electron microscopy
This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
research Complementary and Alternative Medicine Use and Quality of Life among Filipino Adult Psoriasis Vulgaris Patients Seen in a Tertiary Center: A Cross-sectional Study
This study found that complementary and alternative medicine use is common among Filipino adults with psoriasis vulgaris and is linked to poorer quality of life despite adjusting for confounding variables.
research Upadacitinib is effective in treating psoriasis combined with lichen planus: a case report
In this case report, a female patient with both psoriasis and lichen planus initially responded to acitretin and topical mometasone but experienced a relapse after stopping the treatment. The authors reported marked improvement within 3 months after switching to upadacitinib, aiming to guide clinical decision-making.
research Dupilumab and ritlecitinib combination therapy in a patient with alopecia totalis and atopic disease
research Photobiomodulation and alopecia: a crowdsourced survey study on patient preferences
This study surveyed 60 participants via social media to gather insights on patient preferences and experiences with at-home photobiomodulation devices for hair loss, finding that the majority had not previously used such a device.
research Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients
This study reviewed 40 patients with scalp symptoms and identified a new variant of diffuse lichen planopilaris in 20 individuals, suggesting these conditions should be considered in similar cases.
research Effects of the PI3K/Akt signaling pathway on the hair inductivity of human dermal papilla cells in hair beads
This study found that activating the PI3K/Akt signaling pathway in dermal papilla cells enhances their hair-inducing capabilities, suggesting potential strategies for hair regenerative medicine.