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Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.

P2X₃-IR fibers are widespread in rat skin and likely help detect pain.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Pharmacists play a key role in helping patients use over-the-counter products correctly, including those for hair regrowth and smoking cessation.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.

Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.

Botulinum toxin is effectively used to treat various painful conditions and its therapeutic uses are growing.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Repeated use of platelet-rich plasma in rats caused increased pain sensitivity.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.

Oxytocin receptors are found in skin cells near touch and pain neurons.

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Passiflora incarnata may help with anxiety but has risks and drug interactions. There's a genetic link between Fragile X Syndrome and Autism Spectrum Disorder. 6.7% of urine cultures showed hospital-acquired urinary tract infections. Children used screens more during COVID-19, causing various health complaints. Autism Spectrum Disorder is often underdiagnosed in females. Dissociative disorders in childhood sexual abuse victims are more common in males. Most pregnant teenagers are not dissatisfied with their body image but worry about weight. Diagnosing tuberculosis after knee surgery is challenging due to non-specific symptoms. Post-COVID-19 syndrome is more common in older, severely affected patients. Psychiatrists should be part of pain management teams due to the psychological aspects of pain.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

The new method showed that endometriotic tissue has lower estrogen receptor levels but similar progesterone levels compared to normal endometrium, with both following a similar cycle.

Skin has specialized touch receptors that can tell different sensations apart.