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GlossaryTropomyosin receptor kinase A

receptor protein involved in nerve growth and hair follicle health

Tropomyosin receptor kinase A (TrkA) is a protein that plays a crucial role in the development and function of the nervous system. It is a receptor for nerve growth factor (NGF), which is essential for the survival, growth, and maintenance of certain types of neurons. TrkA is also involved in pain perception and can influence hair growth by affecting the health of hair follicles.

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research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature

40 citations, December 2016 in “Journal of Dermatological Treatment”

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia

research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia

6 citations, September 2020 in “Advanced Biology”

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

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