1 citations
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November 2025 in “Journal of Education Health and Sport” This study suggests that cannabinoids, especially CBD, show promise as potential treatments for various inflammatory, infectious, and autoimmune skin diseases, with ongoing research needed to confirm clinical efficacy and safety.
7 citations
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January 2019 in “Headache” This source suggests that migraine prevalence increases in transgender women using oestrogen and decreases in transgender men using testosterone, with high oral oestrogen doses in transgender women potentially linked to aura risk.
September 2024 in “Health Problems of Civilization” This study describes the efficacy of oral isotretinoin in treating severe, hormonal, and treatment-resistant acne, noting significant side effects that depend on dose and duration, including teratogenic risks and common issues like skin dryness, while underscoring the importance of systematic monitoring to mitigate adverse effects.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that structural changes in the TRPV3 channel are linked to severe skin conditions like Olmsted syndrome, with differences observed between heat-activated and resting states.
November 2025 in “Journal of Investigative Dermatology” Keloid fibroblasts cause itch and pain by releasing more histamine.
3 citations
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October 2023 in “Journal of Pain” In this exploratory study of trigeminal neuralgia patients undergoing microvascular decompression surgery, differential protein expression in plasma and cerebrospinal fluid was observed between responders and non-responders, suggesting potential biomarkers to predict surgical success and providing insights into the mechanisms of pain relief.
20 citations
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January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This review discusses lysophosphatidic acid's role in neuropathic pain and cholestatic itch, highlighting its complex signaling pathways, but reports no new clinical results.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.
11 citations
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April 2020 in “Life sciences” In this study, pantothenic acid at 20 μg/ml was observed to promote dermal papilla cell proliferation and migration, likely through up-regulation of ID3 and inhibition of Notch signaling.
April 2023 in “Research Square (Research Square)” This study reported that 57% of healthcare workers experienced persistent post-COVID-19 complications, with common symptoms including hair loss, easy fatigability, mood swings, and anxiety.
February 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” In this rat model of diabetic neuropathic pain, the study found that testosterone metabolites dihydrotestosterone and 3α-diol may have analgesic effects through different mechanisms.
March 2012 in “Journal of The American Academy of Dermatology” Hair casts are often mistaken for head lice, scalp pain in hair loss is linked to certain nerve factors, eyelash growth treatment is safe and effective, and nail shedding in children may follow hand-foot-mouth disease.
4 citations
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November 2018 in “Journal of pharmacological sciences” This study found that low-intensity exercise improved pain relief in aged rats through increased brain allopregnanolone levels, while high-intensity exercise was effective in both adult and aged rats via a different mechanism.
2 citations
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April 2022 in “PLoS ONE” This study reports that short exposure to vibration causes epithelial cells to retract filopodia, concentrate actin at their edges, and increase expression of the protease calpain, suggesting a mechanism for vibration-induced pain relief.
January 2024 in “Editora Científica Digital eBooks” This study highlights the therapeutic benefits of photobiomodulation, which uses light exposure to facilitate tissue repair and prevent inflammation and apoptosis, in treating conditions like arthritis, reumatism, and inflammatory pain, with its complex mechanisms potentially leading to future discoveries and treatments.
1 citations
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July 2020 in “Dermatology” This review discusses the mechanisms, applications, and research evidence of photobiomodulation, highlighting its efficacy, safety, and potential for standardized evaluation methods, but reports no new clinical results.
December 2022 in “Medical lasers” This study reviews the mechanism and potential treatment roles of low-level laser therapy for immune-mediated skin diseases, reporting no new clinical results.
October 2022 in “Journal of ophthalmology” This review discusses the implementation and mechanisms of photobiomodulation therapy in various medical fields, including ophthalmology, and reports no new clinical results.
26 citations
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April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
353 citations
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February 2022 in “Nature Immunology” This review explores post-COVID-19 syndromes and the underlying mechanisms, including persistent inflammation, autoimmunity, and possible viral reservoirs, but reports no new clinical results.
January 2024 in “Wiadomości Lekarskie” This research by Dr. Lester Fehmi suggests that exercises to shift attention from focused to dispersed may enhance alpha wave synchronization in the brain, potentially reducing pain perception.
15 citations
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January 2016 in “Journal of cell science & therapy” This study found that autologous micro-grafts improved wound healing and reduced pain in leg ulcers unresponsive to routine treatments within one week, lasting up to a month.
January 2023 in “Л.Н. Гумилев атындағы Еуразия ұлттық университетінің хабаршысы” This article reviews the clinical applications of botulinum toxin, highlighting its effectiveness in treating various pain conditions like diabetic neuropathy and chronic migraines and noting future research should focus on enhancing safety and efficacy.
23 citations
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June 1950 in “American journal of diseases of children” This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.
10 citations
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July 2021 in “International Journal of Rheumatic Diseases” This review summarizes evidence indicating that body image issues in patients with systemic lupus erythematosus should be addressed with the same importance as physical symptoms like pain and disability.
December 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This case report describes a post-COVID syndrome patient who experienced symptoms like headache, joint pain, and swollen lymph nodes; treatment with Erbisol drugs reportedly alleviated symptoms and normalized immunological parameters.
This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.
71 citations
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February 2020 in “Journal of Translational Medicine” This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.
22 citations
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November 2018 in “Brazilian Journal of Pharmaceutical Sciences” This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.
September 2019 in “Encyclopedia of Life Sciences” This review presents an overview of the integrated organ systems involved in wound healing and reports no new findings; the authors emphasize the roles of blood coagulation, immune response, and cellular mechanisms in tissue repair.