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Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Understanding where cancer cells come from helps create better prevention and treatment methods.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Telocytes might help with skin repair and regeneration.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Stem cell self-renewal is complex and needs more research for full understanding.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Scientists created stem cells that can grow hair and skin.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Mutant mice help researchers understand hair growth and related genetic factors.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Skin has specialized touch receptors that can tell different sensations apart.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Improving the environment and cell interactions is key for creating human hair in the lab.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.

Claudin-1 is important for the barrier function and growth of hair.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.