January 2024 in “Authorea (Authorea)” STK11 gene polymorphism does not predict metformin response in PCOS.
19 citations,
August 2016 in “Health and Quality of Life Outcomes” Metformin helped improve the quality of life for Chinese women with PCOS, especially in physical health and symptoms like infertility, acne, and hair loss.
29 citations,
October 2020 in “Journal of the European Academy of Dermatology and Venereology” Women with high androgen levels may have more severe COVID-19 symptoms.
21 citations,
July 2016 in “Gynecological Endocrinology” Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
150 citations,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
1 citations,
October 2010 in “Cambridge University Press eBooks” Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
55 citations,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
10 citations,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
97 citations,
July 2006 in “Dermatologic therapy” The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
June 2022 in “Biomedical reports” STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.
7 citations,
May 2019 in “Journal of the Formosan Medical Association” HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.
14 citations,
January 2018 in “Endocrinology and Metabolism” Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.
45 citations,
November 2012 The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.
6 citations,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
1 citations,
July 2023 in “Frontiers in Immunology” Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
18 citations,
April 2016 in “Endocrinology and Metabolism Clinics of North America” The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
47 citations,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
46 citations,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
2 citations,
May 2023 in “Current Nutrition Reports” Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.
9 citations,
April 2015 in “Dermatologic Therapy” Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.
50 citations,
January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
135 citations,
April 2017 in “Advances in Clinical and Experimental Medicine” New treatments for PCOS show promise, including both medication and non-medication options.
22 citations,
March 2000 in “Clinical endocrinology” Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.
8 citations,
June 2020 in “The Journal of Clinical Endocrinology and Metabolism” Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
2 citations,
July 2023 in “Frontiers in Endocrinology” The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.
May 2023 in “Journal of Student Research” Creating specific biological indicators is important for early detection and treatment of PCOS.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
January 2025 in “Journal of Education Health and Sport” Metformin helps manage PCOS by improving metabolism and ovulation, but should be part of a personalized treatment plan.