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Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.

Mutations in the P2RY5 gene cause autosomal recessive woolly hair.

Different fibroblasts play key roles in skin healing and scarring.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Horse skin stem cells combined with platelet-rich plasma improve skin healing.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.

Obesity is linked to various skin conditions and issues, and losing weight can improve these conditions.

Red ginseng oil is believed to have various health benefits and is safe, but more research is needed to fully understand how it works.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Healthy lifestyle changes can significantly improve skin health as you age.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

3D cell cultures are better for testing hair growth treatments than 2D cultures.

Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.