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Basonuclin helps identify and track hair follicle development and cycling in mice.

In this study, researchers found that Sox9 is critical for determining whether Nestin⁺ stem cells in adult mouse skin develop into melanocytes or glial cells, offering insights into possible paths for melanoma research.

This study successfully developed 3D hair follicle organoids from neonatal mouse epidermal and dermal cells, showing structural and molecular resemblance to native anagen hair follicles.

In this study, the researchers developed a new protocol using human-induced pluripotent stem cells to efficiently create skin hair follicle organoids, which may aid in optimizing hair follicle growth and exploring treatments for alopecia.

This review explores the complex interactions of intrinsic and extrinsic mechanisms that regulate hair follicle stem cells and their role in skin homeostasis, aiming to advance understanding that could support future research on skin disorders.

This study introduces a new method to isolate stem cells from the hair follicle outer root sheath of equine skin, demonstrating that these cells, named eMSCORS, proliferate efficiently and can differentiate similarly to adipose tissue-derived MSCs, offering a promising alternative for equine veterinary applications.

This study found that the cosmetic olfactory receptor agonist cyclohexyl salicylate may stimulate hair growth and expand stem cell progeny, suggesting potential as a cosmetic adjuvant for hair loss.

In this study, researchers identified hair follicle stem cells in the bulge region of canine hair follicles, suggesting potential applications for future translational research.

In this study, researchers found two distinct stem cell reservoirs in human hair follicles that require mesenchymal cells for stem cell proliferation.

This review explores hypotheses about hair follicle stem cell function in morphogenesis and cycling, highlights the importance of dermal papilla cells and signaling pathways, and provides no new clinical findings.

This study explored the potential of the lysate and lipoteichoic acid from Lactiplantibacillus plantarum APsulloc 331261 to improve scalp seborrheic dermatitis by modulating inflammatory and lipogenesis pathways in vitro, suggesting potential as a natural treatment option.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

Basonuclin is crucial for hair follicle development and cycling in mice.

This study found that human embryonic and induced pluripotent stem cells differentiated into specific bulge stem cells and successfully formed new hair follicles when transplanted with mouse dermal cells in immunodeficient mice.

This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.

In this study, the antibody A3 identified quiescent post-progenitor epithelial and mesenchymal cells in developing rat hair follicles, suggesting it may help track the differentiation of these cells.

This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.

In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.

Calretinin identifies the companion cell layer in human hair follicles.

This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.

In this study, researchers isolated multipotent stem cells from elderly human epidermis and showed that they could differentiate into neurons using TAT-VHL peptide, suggesting potential for regenerative therapies.

In this study, L-threonate was observed to inhibit DHT-induced DKK-1 expression in dermal papilla cells and reverse DHT's inhibitory effects on outer root sheath cell growth, suggesting potential as a treatment for androgen-driven balding.

This review discusses transplantation of melanocyte stem cells for vitiligo treatment and reports no new clinical results; it suggests the procedure could be effective in reactivating melanocyte precursors for repigmentation.

This study observed that dandruff-affected scalp skin has increased T-cell infiltration in the epidermis and a reduction in the hair follicle's physiological immune privilege, particularly in the suprabulbar outer root sheath area, indicating a distinct immune microenvironment compared to healthy scalp.

This study suggests that follicular stem cells in the bulge region are not directly targeted in androgenetic alopecia, based on the consistent presence of cytokeratin 15 across scalp samples from affected patients.

This study found that patients with alopecia areata have lower levels of sCD83, a protein which, when supplemented in a mouse model, reversed disease symptoms and supported regulatory T cell proliferation, possibly by interacting with IDO activity.

Stem cells in developing hair follicles move to specific areas as they mature.

This study found that K15 is variably expressed in sheep and mouse hair follicles, with specific patterns suggesting a role in the early stages of keratinocyte differentiation.