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This study observed that PAI-2 is consistently expressed in differentiating cells of murine hair and nail, suggesting it may function as a marker of differentiation and possibly protect against premature cell death.

This study found HLA and beta 2-microglobulin antigens in various skin structures, with specific localization patterns in keratinocytes and hair follicle components, but not in eccrine or apocrine glands.

This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.

This study found that basal cell carcinoma exhibits patterns of hair follicle differentiation but is stuck in telogen arrest, which can be rescued by adding noggin and TGF-β2 in vitro.

This article reviews the molecular interactions involved in hair follicle cycling and highlights the role of dermal papilla cells, but it presents no new research findings.

This case report describes a basal cell carcinoma arising in association with a vellus hair cyst, which the authors note has not been previously reported.

In this study, researchers demonstrated that follicular tight junctions in porcine skin form a barrier to nanoparticle penetration, particularly in upper regions, which supports its use as a model for human skin.

This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.

This study observed that the glassy layer of hair follicles in guinea pigs consists of thick collagen-type fibrils organized into two distinct arrays, whereas in young mice, the fibrils are thinner and develop between the outer root sheath and fibroblasts.

This study found that transgenic mice expressing HPV E6/E7 in the outer root sheath experience continuous hair follicle cycling due to delayed catagen entrance and insensitivity to telogen resting signals.

This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.

This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.

In this study, high concentrations of dihydrotestosterone and testosterone reduced the growth of human hair follicle cells in vitro, while high estradiol levels increased their growth.

This laboratory study found that collagen matrices with high-sulfated hyaluronan may enhance the cultivation of human keratinocytes and melanocytes from hair follicles for epidermal graft development.

This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.

This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.

This review suggests that the inner root sheath of human hair follicles may have broader regulatory roles beyond structural support, potentially impacting processes like folliculogenesis, anagen phase regulation, and immunomodulation.

This study found that involucrin likely plays a key role in forming the cornified material of the medulla and inner root sheath of human hair, contributing to its mechanical strength.

This study showed that in C3H/HeJ mice, focal follicular inflammation starts before overt hair loss, with inflammation severity possibly reaching a threshold causing hair follicle dystrophy prior to visible hair loss.

This study provides evidence for K1 and K10 derivatives' presence in the inner root sheath and hair cuticle, suggesting that these hair follicle parts may follow familiar keratinization principles.

This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.

This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.

This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.

This study found that the distribution of carbohydrates and proteins in porcine hair follicles and sebaceous glands showed minor differences compared to humans.

This study found that scalp cooling markedly reduces cellular uptake of anthracycline drugs in human keratinocytes, partially explaining its protective effect against chemotherapy-induced cytotoxicity.

This study found that certain concentrations of sodium fluoride accelerated apoptosis in cultured human hair follicles, while sodium selenite could counteract this toxicity in vitro.

This study found that a truncated region of the K5 promoter directs expression in stratified epithelia, particularly in epidermis, hair follicles, and tongue, potentially involving specific keratinocyte nuclear proteins in regulation.