research Mitogen-Regulated Protein/Proliferin mRNA Induction Following Single Applications of Tumor Promoters to Murine Skin
mrp/plf-mRNA can indicate tumor-promoting effects in skin.
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30-60 / 361 resultsresearch Dynamic Expression of Ornithine Decarboxylase in Hair Growth
Ornithine decarboxylase is crucial for hair growth and follicle development.
research Induction of Ornithine Decarboxylase Activity in Hairless Rat Epidermis as a Pharmacological Model: Validation of the Animal Model
Female rats aged 8 weeks are best for this model.
research The Role of MEK and Antizyme in Keratinocyte Stem Cell Expansion and Differentiation
Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.
research Ornithine Decarboxylase as a Target for Chemoprevention of Basal and Squamous Cell Carcinomas in Ptch1+/– Mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice
Dimethylarsinic acid speeds up skin tumor growth in certain mice.
research K6/ODC Transgenic Mice as a Sensitive Model for Carcinogen Identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
research Heterogeneity of Ornithine Decarboxylase Expression in 12-O-Tetradecanoylphorbol-13-Acetate-Treated Mouse Skin and in Epidermal Tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
research Synergy of Eflornithine Cream with Laser and Light-Based Systems for Hair Management
Using Eflornithine cream with laser treatments improves facial hair removal.
research Comprehensive Clinical Management of Hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
research Ornithine Decarboxylase Activity in Relation to DNA Synthesis in Mouse Interfollicular Epidermis and Hair Follicles
research Contemporary Medical Therapy for Polycystic Ovary Syndrome
New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
research Association of a Polymorphism in the Ornithine Decarboxylase Gene with Male Androgenetic Alopecia
research Bachmann–Bupp Syndrome and Treatment
DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
research Serendipity in Trichology
Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.
research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome
Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.
research Studies on Enzyme Activities in the Hair Root in Male Pattern Baldness: Glycolytic Enzyme, Acid Hydrolase, Transglutaminase and Ornithine Decarboxylase Activities of Plucked Hair Roots
research Capryloyl Glycine And Soy Isoflavonoids In Hypertrichosis: An Experimental And Placebo-Controlled Clinical Study
The cream effectively reduced hair growth on forearms.
research Excess Hair: Physical And Pharmacological Treatments
Laser and Eflornithine are more effective for hair removal than traditional methods.
research Induction of Dark Keratinocytes by 12-O-Tetradecanoyl-Phorbol-13-Acetate and Mezerein as an Indicator of Tumor-Promoting Efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research Increased Hair Polyamine Levels in Patients with Alzheimer's Disease
Alzheimer's patients have higher levels of certain chemicals in their hair.
research Hirsutism And Virilism
Hirsutism treatments can slow new hair growth, but existing hair needs removal, and eflornithine helps reduce hair growth.
research Cutaneous Application of Alpha-Methylspermidine Activates the Growth of Resting Hair Follicles in Mice
Putting α-methylspermidine on mouse skin can start hair growth.
research Cutaneous Metabolism of Vitamin B-6
An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Stress and the Skin: Significance of Emotional Factors in Dermatology
Stress affects skin health and emotional well-being should be considered in skin disease treatment.
research Treatment of Hirsutism and Acne in Hyperandrogenism
Medicines that lower androgen levels and hair removal treatments help manage excessive hair and acne in women with PCOS.
research Overexpression of Spermidine/Spermine N1-Acetyltransferase Under the Control of Mouse Metallothionein I Promoter in Transgenic Mice: Evidence for a Striking Post-Transcriptional Regulation of Transgene Expression by a Polyamine Analogue
Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.
research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.